Results 41 to 50 of about 2,027,311 (293)

Continual Learning for Multimodal Data Fusion of a Soft Gripper

Advanced Robotics Research, EarlyView.
Models trained on a single data modality often struggle to generalize when exposed to a different modality. This work introduces a continual learning algorithm capable of incrementally learning different data modalities by leveraging both class‐incremental and domain‐incremental learning scenarios in an artificial environment where labeled data is ...
Nilay Kushawaha, Egidio Falotico
wiley   +1 more source

A Site‐Aware Representation Learning Framework For Unified Molecular Interaction Modeling and Generative Design

Advanced Science, EarlyView.
MolDBG is a site‐aware, sequence‐only framework that unifies drug‐target affinity prediction, binding‐site identification, and affinity‐conditioned molecular generation for structured proteins. Guided by multi‐task binding‐site supervision, it aligns interaction‐critical residues before learning drug‐target representations and simultaneously infers ...
Gang Luo, Qianqian Zhang, Chenhao Wang, Zhiheng Yi, Alex Jinpeng Wang, Jing Tang, Min Li   +6 more
wiley   +1 more source

Fast and Fine Location of Total Lightning from Low Frequency Signals Based on Deep-Learning Encoding Features

Remote Sensing, 2021
Lightning location provides an important means for the study of lightning discharge process and thunderstorms activity. The fine positioning capability of total lightning based on low-frequency signals has been improved in many aspects, but most of them ...
Jingxuan Wang, Yang Zhang, Yadan Tan, Zefang Chen, Dong Zheng, Yijun Zhang, Yanfeng Fan   +6 more
doaj   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

Advanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English, Dorothea Böken, Matthew W. Cotton, Matthew R. Cheetham, Johanna S. Jackson, Georg Meisl, John S. H. Danial, Paul M. Matthews, Nurun N. Fancy, David Klenerman   +9 more
wiley   +1 more source

Statistical estimation of locations of lightning events [PDF]

Journal of Geophysical Research: Atmospheres, 1999
In this paper, a statistical approach to the retrieval of lightning locations is proposed for the first time. This novel approach views the errors of the time measurements as random variables rather than unknown numbers. The unknown location (x, y, z) as well as the standard deviation σ of the errors are treated as unknown parameters of a statistical ...
Pensky, Marianna, Cannon, John R.
openaire   +4 more sources

Statistical patterns in the location of natural lightning [PDF]

Journal of Geophysical Research, 2012
Lightning discharges are nature's way of neutralizing the electrical buildup in thunderclouds. Thus, if an individual discharge destroys a substantial fraction of the cloud charge, the probability of a subsequent flash is reduced until the cloud charge separation rebuilds.
F. G. Zoghzoghy, M. B. Cohen, R. K. Said, U. S. Inan   +3 more
openaire   +3 more sources

YTHDC1 Orchestrates Glucose and Glutamate Rewiring to Overcome Lethal Metabolic Stress in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Lai et al. find that m6A reader YTHDC1 is specifically overexpressed in triple‐negative breast cancer (TNBC) and orchestrates glucose and glutamine metabolism in an m6A‐dependent manner to confer robust adaptability to lethal metabolic stress. Leveraging YTHDC1 knockdown‐induced metabolic vulnerability, an ATF4 mRNA‐targeted nanotherapy is developed to
Zheng‐Hao Lai, Yi Wang, Na‐Na Li, Ling Zeng, Renzhong Liu, Xue Li, Cheukfai Li, Xin‐Yu Ma, Wenkui Fu, Yingsen Tang, Jinjin Chen, Ning Liao, Man‐Li Luo   +12 more
wiley   +1 more source

Phillip Lightning interview

, 1975
8 p. transcript of an interview with Phillip Lightning conducted by Richard Lightning on April 11, 1975. Tape number IH-191, transcript disc 38.Tells stories from his father and grandfather of the signing of Treaty #6 and of Indian life before that time ...
Lightning, Richard, Lightning, Phillip
core   +1 more source

Transmission-Lightning-Arrester : A Location Determination Using Tflash [PDF]

, 2017
The high density of lightning occurrence in Malaysiahas caused problems to transmission and distribution electricalenergy. Normally, transmission overhead lines trip due to BackFlashover (BF) of lightning and shielding failures of earth wire.Therefore, a
Ramly, M. E.; Tenaga Nasional Berhad, Sidik, M. A. B.; Universitas Sriwijaya, Buntat, Zolkafle; Universiti Teknologi Malaysia, Jambak, M. I.; Universitas Sriwijaya, Arief, Y. Z.; Universitas Sriwijaya, Ramli, Z; Tenaga Nasional Berhad, Kurnia, R. F.; Universitas Sriwijaya, Wahab, A. A.; Tenaga Nasional Berhad, Nawawi, Z.; Universitas Sriwijaya   +8 more
core   +1 more source

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

Advanced Science, EarlyView.
Tau populations with different aggregation states associate with distinct sets of proteins in the Alzheimer's disease brain. Proteomic discovery combined with single‐molecule analysis in neurons reveals dynamic associations involving proteostasis, metabolism and RNA biology.
Dorothea Böken, Paula Beltran Lobo, Yunzhao Wu, Lyla A. Rowe, Emre Fertan, Cara L. Croft, Maria Jimenez‐Sanchez, Dezerae Cox, David Klenerman   +8 more
wiley   +1 more source