Results 41 to 50 of about 11,683 (259)

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

A Fast and Fine‐Resolution Location Method for Lightning Channels Based on Time Series Segmented Feature of Low Frequency Signal

Earth and Space Science
Most real‐time lightning location systems are based on feature matching to locate lightning, but they often lack the ability to locate lightning channels.
Jingxuan Wang, Yang Zhang, Yanfeng Fan, Yijun Zhang, Dong Zheng, Weitao Lyu   +5 more
doaj   +1 more source

Lightning Occurrence between 2016 and 2020 in Fusagasugá, Cundinamarca, Colombia

Ingeniería
Context: Lightning is a powerful natural phenomenon that poses a risk to life and infrastructure, given the enormous amounts of energy it can transfer in short periods of time, especially in cloud-to-ground strikes.
Fernando Díaz-Ortiz, Neyder Perilla López, Juan Pablo Ospina Carrillo, Pedro Cifuentes Guerrero   +3 more
doaj   +1 more source

Leading the Pack: Next‐Generation Batteries for Humanoid Robotics

Advanced Science, EarlyView.
Humanoid robots challenge traditional and anticipated energy technologies. Humanoid robot benchmarks of runtimes and energy demands for industry applications inform humanoid robot battery design choices at the cell level, pack level, and system level.
Matthew Bergschneider, Jiaqi Ke, Jin Luo, Laisuo Su, Thomas Campbell, Yue Zhou, Kyeongjae Cho   +6 more
wiley   +1 more source

Upgraded Low-Frequency 3D Lightning Mapping System in North China and Observations on Lightning Initiation Processes

Remote Sensing
The three-dimensional (3D) low-frequency lightning mapping system (LF-LMS) in north China has been updated. The lightning electric field derivative (dE/dt) sensor and continuous acquisition mode has been newly designed to ensure a capability of entire ...
Mingyuan Liu, Xiushu Qie, Zhuling Sun, Rubin Jiang, Hongbo Zhang, Ruiling Chen, Shanfeng Yuan, Yu Wang, Xiangke Liu   +8 more
doaj   +1 more source

A source location algorithm of lightning detection networks in China [PDF]

Annales Geophysicae, 2010
Fast and accurate retrieval of lightning sources is crucial to the early warning and quick repairs of lightning disaster. An algorithm for computing the location and onset time of cloud-to-ground lightning using the time-of-arrival (TOA) and azimuth ...
Z. X. Hu, W. G. Zhao, H. P. Zhu
doaj   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

Advanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo, Yu He, Shuyao Li, Haoyu Guan, Ruili Cui, Yu Shi, Zhongwen Jiang, Siyu Wang, Xuan Li, Jiyuan Li, Mei Hu, Yupeng Zhou, Beisha Tang, Yanyan Zhang, Zhaobing Gao, Yu Zhou, Zhenhua Liu, Ping Li   +17 more
wiley   +1 more source

Thermal Deformation Correction for the FY-4A LMI

Remote Sensing
Affected by solar radiation in space, the FY-4A Lightning Mapping Imager (LMI) detection array exhibits daily periodic thermal expansion and contraction, leading to deviations in lightning positioning accuracy.
Yuansheng Zhang, Xiushu Qie, Dongjie Cao, Shanfeng Yuan, Dongfang Wang, Hongbo Zhang, Dongxia Liu, Zhuling Sun, Mingyuan Liu, Kexin Zhu, Rubin Jiang, Jing Yang   +11 more
doaj   +1 more source

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

Advanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan, James R. M. Black, Carlos Martínez‐Ruiz, Kristiana Grigoriadis, Jasmin Fisher, Nicholas McGranahan   +5 more
wiley   +1 more source

Advances of Observation and Study on Tall-object Lightning in Guangzhou over the Last Decade

应用气象学报, 2020
Comparing to the ground or low-object, tall-object is more likely to reach the threshold for the initiation of leader on its top due to the distortion and enhancement of electric field, therefore tall-object is not only easier to get struck by downward ...
Lü Weitao, Chen Lüwen, Ma Ying, Qi Qi, Wu Bin, Jiang Ruijiao   +5 more
doaj   +1 more source