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Hypersensitivity Reaction to Lignocaine

Journal of The Royal Naval Medical Service, 1971
AbstractA case is described of a hypersensitivity reaction resulting from the administration of a dental local anaesthetic.
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The neuromuscular effects of lignocaine

General Pharmacology: The Vascular System, 1984
The local anesthetic drug lignocaine, in concentrations which completely block both nerve and muscle action potentials, produces concentration-dependent contractures in the vertebrate skeletal and smooth muscle fibres. The contractures produced by lignocaine were not related to membrane depolarization.
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Clinical Pharmacokinetics of Lignocaine

Clinical Pharmacokinetics, 1978
Lignocaine is widely used as a local anaesthetic and antiarrhythmic drug. It is commonly administered to patients with acute myocardial infarction as prophylaxis for ventricular fibrillation, although its efficacy in preventing primary ventricular fibrillation is still debated.
W. Meister, Neal L. Benowitz
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Contact sensitivity to lignocaine

Clinical and Experimental Dermatology, 1993
Lignocaine is a rare contact allergen, in contrast to other local anaesthetics such as benzocaine, which commonly sensitize. The case of a patient sensitized to lignocaine through the use of a topical medication for the treatment of haemorrhoids is reported.
E. Cronin, S.E. Handfield-Jones
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