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The Advanced LIGO Photon Calibrators [PDF]

open access: yesReview of Scientific Instruments, 2016
The two interferometers of the Laser Interferometry Gravitaional-wave Observatory (LIGO) recently detected gravitational waves from the mergers of binary black hole systems.
A. J. Weinstein   +29 more
core   +10 more sources

Exploring Low‐Intensity Focused‐ultrasound Neuromodulation in Alzheimer's Disease [PDF]

open access: yesAlzheimers Dement
Abstract Background Alzheimer's disease (AD) presents a major public health challenge with few effective therapeutic options. Monoclonal antibodies targeting β‐amyloid show promise, but their clinical efficacy remains modest. As such, combining pharmacological and non‐pharmacological interventions to slow cognitive decline has become a key area of ...
Rezai A   +6 more
europepmc   +2 more sources

Advanced LIGO [PDF]

open access: yesClassical and Quantum Gravity, 2015
The Advanced LIGO gravitational wave detectors are second generation instruments designed and built for the two LIGO observatories in Hanford, WA and Livingston, LA. The two instruments are identical in design, and are specialized versions of a Michelson interferometer with 4 km long arms.
Aasi, J.   +326 more
openaire   +12 more sources

Combination of focused ultrasound blood‐brain barrier opening with Lecanemab therapy in mild Alzheimer's disease [PDF]

open access: yesAlzheimers Dement
Abstract Background Alzheimer's disease (AD) is a major neurodegenerative disorder affecting millions worldwide, with limited treatment options and significant challenges in drug delivery. Monoclonal antibody (mAb) therapies targeting β‐amyloid plaques have shown promise but are constrained by potential adverse effects, including amyloid‐related ...
Rezai A   +9 more
europepmc   +2 more sources

Cosmic Explorer: A Next-Generation Ground-Based Gravitational-Wave Observatory

open access: yesGalaxies, 2022
Cosmic Explorer is a concept for a new laser interferometric observatory in the United States to extend ground-based gravitational-wave astrophysics into the coming decades.
Evan D. Hall 
doaj   +1 more source

Advanced LIGO Laser Systems for O3 and Future Observation Runs

open access: yesGalaxies, 2020
The advanced LIGO gravitational wave detectors need high power laser sources with excellent beam quality and low-noise behavior. We present a pre-stabilized laser system with 70 W of output power that was used in the third observing run of the advanced ...
Nina Bode   +13 more
doaj   +1 more source

Determination of absolute expression profiles using multiplexed miRNA analysis. [PDF]

open access: yesPLoS ONE, 2017
Accurate measurement of miRNA expression is critical to understanding their role in gene expression as well as their application as disease biomarkers. Correct identification of changes in miRNA expression rests on reliable normalization to account for ...
Yunke Song   +10 more
doaj   +1 more source

Adapting LIGO workflows to run in the Open Science Grid

open access: yesSoftwareX, 2021
During the first observation run the LIGO collaboration needed to offload some of its most, intense CPU workflows from its dedicated computing sites to opportunistic resources.
Edgar Fajardo   +7 more
doaj   +1 more source

GstLAL: A software framework for gravitational wave discovery

open access: yesSoftwareX, 2021
The GstLAL library, derived from Gstreamer and the LIGO Algorithm Library, supports a stream-based approach to gravitational-wave data processing. Although GstLAL was primarily designed to search for gravitational-wave signatures of merging black holes ...
Kipp Cannon   +30 more
doaj   +1 more source

The advanced LIGO input optics [PDF]

open access: yesReview of Scientific Instruments, 2016
The advanced LIGO gravitational wave detectors are nearing their design sensitivity and should begin taking meaningful astrophysical data in the fall of 2015. These resonant optical interferometers will have unprecedented sensitivity to the strains caused by passing gravitational waves. The input optics play a significant part in allowing these devices
Chris L. Mueller   +22 more
openaire   +5 more sources

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