Results 41 to 50 of about 828,317 (269)

Obtaining Reliable Likelihood Ratio Tests from Simulated Likelihood Functions [PDF]

open access: yesPLoS ONE, 2014
Models allowing for continuous heterogeneity by assuming that value of one or more parameters follow a specified distribution have become increasingly popular. This is known as 'mixing' parameters, and it is standard practice by researchers--and the default option in many statistical programs--to base test statistics for mixed models on simulations ...
openaire   +6 more sources

Tests for Global Maximum of the Likelihood Function [PDF]

open access: yesProceedings. (ICASSP '05). IEEE International Conference on Acoustics, Speech, and Signal Processing, 2005., 2006
Given a relative maximum of the log-likelihood function, how to assess whether it is the global maximum? This paper investigates a statistical tool, which answers this question by posing it as a hypothesis testing problem. A general framework for constructing tests for the global maximum is given.
Doron Blatt, Alfred O. Hero III
openaire   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Advanced Survival Analysis of Competing Risks Data Under Block Type-I Hybrid Censoring in Multiple Testing Environments

open access: yesIEEE Access
When experimental units are subject to more than one possible cause of failure, the resulting observations are referred to as competing risks data. Classical analytical methods are well suited for handling such data when they originate from a single ...
Refah Alotaibi, Mazen Nassar
doaj   +1 more source

Maximum likelihood distance estimation algorithm for multi-carrier radar system

open access: yesThe Journal of Engineering, 2019
In this study, a maximum likelihood distance estimation algorithm is proposed for a multi-carrier radar system to estimate the time delay of non-integer sampling intervals. Particularly, the equivalent relationship between time domain delay and frequency
Yue Chen   +4 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Statistical tests in particle physics

open access: yesRevista de Investigación de Física
Particle physics emerged as a pioneer discipline in "big science"; experiments are being carried out in accelerators that are increasing in energy and complexity by the collaborations of thousands of physicists from hundreds of institutes in a few dozen ...
Mississippi Valenzuela
doaj   +1 more source

Improved multi-target tracking algorithm based on SMC-CBMeMBer for the airborne Doppler radar

open access: yesThe Journal of Engineering, 2019
To effectively suppress clutter in airborne Doppler radar and improve multi-target tracking (MTT) performance, this study proposes an improved MTT algorithm based on Sequential Monte Carlo Cardinality Balanced Multi-target Multi-Bernoulli (SMC-CBMeMBer ...
Muyang Luo   +4 more
doaj   +1 more source

CMB likelihood functions for beginners and experts [PDF]

open access: yesConference on 3K cosmology, 1999
Although the broad outlines of the appropriate pipeline for cosmological likelihood analysis with CMB data has been known for several years, only recently have we had to contend with the full, large-scale, computationally challenging problem involving both highly-correlated noise and extremely large datasets ($N > 1000$). In this talk we concentrate
Jaffe, A, Bond, JR, Ferreira, P, Knox, L
openaire   +4 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

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