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Journal of International Medical Research, 2022 Autoimmune limbic encephalitis is an antibody-mediated brain inflammatory process, which typically involves the medial temporal lobe. Diagnosis requires the presence of antineuronal antibodies, but sometimes patients present clinical features of limbic ...
Viviana Lo Buono +9 more
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Frontiers in Neurology, 2022 PurposeLimbic encephalitis is an increasingly recognized cause of medial temporal lobe epilepsy (mTLE) and associated cognitive deficits, potentially resulting in hippocampal sclerosis (HS).
Attila Rácz +10 more
doaj +2 more sources
Case Report: Anti-LGI1 Limbic Encephalitis Associated With Anti-thyroid Autoantibodies [PDF]
Frontiers in Neurology, 2021 Anti-LGI1 encephalitis is an autoimmune encephalitis with antibodies against leucine-rich glioma-inactivated 1 (LGI1), first described in 2010. It is a non-frequent and poorly understood entity that represents the second most frequent cause of autoimmune
Ricardo Otiniano‐Sifuentes +4 more
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Case Report: Limbic encephalitis following treatment with durvalumab for small-cell lung cancer. [PDF]
Front Immunol, 2023 Background Durvalumab is an immune checkpoint Inhibitor (ICIs) that is used in the treatment of malignant tumors, such as lung cancer and melanoma. ICIs are associated with immune-related adverse events including autoimmune encephalitis, although both ...
Moss TT +7 more
europepmc +2 more sources
Retrograde Amnesia in LGI1 and CASPR2 Limbic Encephalitis: Two Case Reports and a Systematic Literature Review. [PDF]
Eur J NeurolBoth anterograde and retrograde amnesia can typically co‐occur in limbic autoimmune encephalitis (LAE), including the forms associated with antibodies to CASPR2/LGI1, two protein complexed with the voltage‐gated potassium channel (VGKC).
Antonio M +13 more
europepmc +2 more sources
Claustrum sparing sign in seronegative limbic encephalitis [PDF]
eNeurologicalSci, 2023 Background: Limbic encephalitis (LE) is a rare variant of autoimmune encephalitis. It often manifests with subacute neuropsychiatric symptoms of agitation, delusions, variable seizure semiology, and short-term memory loss.
Abeer Sabry Safan +5 more
doaj +2 more sources
Journal of Medical Case Reports, 2021 Background Limbic encephalitis (LE), a variant of autoimmune encephalitis, is inflammation of the limbic system of the brain. The disorder presents with subacute impairment of short-term memory, psychiatric manifestations, confusion and seizures ...
Ismail Ibrahim Ismail +2 more
doaj +2 more sources
Definitions, 2020 The term ‘limbic encephalitis’ (LE) describes the condition when limbic areas of the brain are inflamed (swollen) and consequently not functioning properly. The main regions of the limbic system include the hippocampus and amygdala.
S. Irani, Camilla Buckley
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Diagnosing autoimmune limbic encephalitis [PDF]
Canadian Medical Association Journal, 2019 KEY POINTS Autoimmune limbic encephalitis (ALE) is an inflammatory disease involving the medial temporal lobes; it classically presents with rapid neuropsychiatric decline. Patients with ALE have, and may present with, a diverse array of neuropsychiatric symptoms, which means that they may ...
Adrian, Budhram +3 more
openaire +3 more sources
Autoimmune limbic encephalitis: A manifestation of systemic lupus erythematosus in the central nervous system [PDF]
Dementia & Neuropsychologia, 2015 Autoimmune limbic encephalitis (ALE) associated with systemic lupus erythematosus (SLE) is a rare entity with few reports in the literature to date. In general, ALE associated with SLE has a satisfactory response to immunosuppressive treatment (RIT), but
Débora Bartzen Moraes Angst +5 more
doaj +2 more sources