Results 41 to 50 of about 135,182 (282)

EGFR in Limbo [PDF]

open access: yesCell, 2012
The epidermal growth factor receptor (EGFR) is normally activated by ligand-induced dimerization. Oncogenic mutations in EGFR promote activation in a largely ligand-independent manner. Shan et al. uncover a partially disordered state of EGFR kinase, providing evidence that oncogenic mutations counteract this intrinsic structural instability to promote ...
Eck, Michael J., Hahn, William C.
openaire   +2 more sources

Poly(2‐Oxazoline)‐Based Polyphotoacids: Synthesis, Solution Behavior, and Cellular Uptake of Multi‐Responsive Intracellular Transporters

open access: yesMacromolecular Rapid Communications, EarlyView.
The ability of photoacids to increase their acidity in response to light irradiation (excited state proton transfer, ESPT) makes them attractive building blocks for the design of stimuli‐responsive copolymers. In this contribution, we present highly biocompatible polyphotoacids based on poly(2‐oxazoline)s bearing 1‐hydroxypyrene units. Low cytotoxicity,
Leonid I. Kaberov   +7 more
wiley   +1 more source

Encapsulation for Practical Simplification Procedures [PDF]

open access: yes, 2003
ACL2 was used to prove properties of two simplification procedures. The procedures differ in complexity but solve the same programming problem that arises in the context of a resolution/paramodulation theorem proving system. Term rewriting is at the core
Matlin, Olga Shumsky, McCune, William
core   +2 more sources

Navigating the Rapids: How Non‐Governmental Organization Managers Develop Strategic Adaptation to Repressive Political Environments

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT This article explores the management adaptation strategies non‐governmental organizations (NGOs) managers employ in order to operate in repressive political environments. It answers the question: how do NGO managers initiate, manage and sustain internal change when the political/regulatory environment changes?
Charles Kaye‐Essien   +2 more
wiley   +1 more source

The policy gap – research communication in limbo in South Africa's new Green Paper [PDF]

open access: yes, 2012
South Africa has a shiny new Green Paper on Post-School Education. However policy weary we might be, this is, refreshingly, a good document, with the right ambitions for the overdue overhaul of the higher and further education sector.
Gray, Eve
core  

Analysis of Software Binaries for Reengineering-Driven Product Line Architecture\^aAn Industrial Case Study

open access: yes, 2015
This paper describes a method for the recovering of software architectures from a set of similar (but unrelated) software products in binary form. One intention is to drive refactoring into software product lines and combine architecture recovery with ...
Blech, Jan Olaf   +5 more
core   +2 more sources

Football and the Cyprus conflict [PDF]

open access: yes, 2010
This essay looks at football's role in the Cyprus conflict since Turkish Cypriot clubs broke away from the Cyprus Football Association in 1955. Studying the history of football in the context of the isolation of the Turkish Cypriots after the island's ...
Menary, Steve
core   +1 more source

Isolation, Insularity and Resilience: A Review of the Geophysical, Socioeconomic, and Environmental Vulnerabilities of Gran Canaria and Lesvos Islands for Policy Interventions to Global Change

open access: yesSustainable Development, EarlyView.
ABSTRACT The dynamic nature of small islands being geographically isolated and their perceived connectedness with global networks complicates research attempts to draw general conclusions on whether insularity leads to marginalization or strengthens their resilience for sustainable development.
Toheeb Lekan Jolaosho   +2 more
wiley   +1 more source

Morfologia e distribuição de galhas foliares de Anacardium occidentale L. (Anacardiaceae)

open access: yesJournal of Bioenergy and Food Science, 2015
Galhas são estruturas que exibem associações específicas entre o indutor e a planta hospedeira, onde são evidenciadas modificações morfológicas, anatômicas e químicas dos tecidos vegetais.
Claudia Scareli-Santos   +3 more
doaj   +1 more source

Modelling practical certainty and its link with classical propositional logic [PDF]

open access: yes, 2013
We model practical certainty in the language of accept & reject statement-based uncertainty models. We present three different ways, each time using a different nature of assessment: we study coherent models following from (i) favourability assessments, (
De Cooman, Gert, Van Camp, Arthur
core   +1 more source

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