Results 51 to 60 of about 14,130 (200)

Review: Adolescents' perspectives on and experiences with post‐primary school‐based suicide prevention as end‐users, co‐creators and peer helpers – a systematic review meta‐ethnography

open access: yesChild and Adolescent Mental Health, EarlyView.
Background Suicide is the fourth leading cause of death in adolescents globally. Post‐primary school‐based suicide prevention (PSSP) interventions are an evidence‐based suicide prevention strategy. However, adolescents' experiences with PSSP interventions are not well understood but are arguably critical to ensuring PSSP interventions have their ...
Eibhlin H. Walsh   +3 more
wiley   +1 more source

Junctional Adhesion Molecule‐A (JAM‐A) Associates With High‐Risk Disease in Multiple Myeloma Patients and a Structure‐Based Rationally‐Designed Peptide Inhibitor Attenuates Tumorigenic Features In Vitro and In Vivo

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Multiple myeloma (MM) is an incurable malignancy of terminally‐differentiated plasma cells that represents a major clinical challenge despite unprecedented therapeutic advances, particularly for patients with cytogenetically‐defined high‐risk MM (HR‐MM).
Niamh McAuley   +10 more
wiley   +1 more source

SKY92 Identifies High‐Risk Newly Diagnosed Multiple Myeloma With Inferior Progression‐Free Survival and Implicates NUF2 as a Candidate Driver

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objectives To determine the prevalence and prognostic significance of the SKY92 gene‐expression signature, evaluate minimal/measurable residual disease (MRD), and identify molecular drivers of high‐risk disease in transplant‐eligible newly diagnosed multiple myeloma (TE‐NDMM) patients in the Republic of Ireland.
Roisin M. McAvera   +24 more
wiley   +1 more source

Inter‐organisational projects as complex timescapes: Towards a process theory of temporal complexity

open access: yesEuropean Management Review, EarlyView.
Abstract Inter‐organisational projects (IOPs) are a core organisational form through which complex, cross‐sectoral and cross‐boundary collaboration is coordinated and enacted across organisations and society. As a prevalent form of temporary organising, IOPs bring together diverse actors operating within distinct and often incompatible temporal ...
Catriona M. Burke, Michael J. Morley
wiley   +1 more source

Functional and transcriptomic analyses in Neurospora crassa reveal a crucial role for the N‐glycoprotein deglycosylation process in fungal homeostasis

open access: yesThe FEBS Journal, EarlyView.
In Neurospora crassa, a cytosolic GH18 endo‐β‐n‐acetylglucosaminidase (ENGase) functions as an active deglycosylating enzyme. Deletion of this severely alters tolerance to multiple stress conditions and causes extensive transcriptomic reprogramming, including upregulation of a GH20 exo‐β‐n‐acetylhexosaminidase under ER stress, indicating that N. crassa
Anastasios Samaras   +3 more
wiley   +1 more source

The Effects of Self-Control Failures on Risky Credit Card Usage

open access: yesMarketing Management Journal, 2014
Self-control theory offers insights for explaining why consumers resist or succumb to buying urges. We examine self-control failures in terms of behavioral, psychological, and social constructs and assess their impact on credit card debt by college ...
LUCRETIA LIMERICK, JAMES W. PELTIER
doaj   +1 more source

Incidence of P200 pemphigoid: A nationwide study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The anti‐LAMB4 cell‐based immunoassay is a new serological technique that is far superior to dermal immunoblotting for detecting autoantibodies directed against the P200 protein. This method allows a re‐evaluation of the incidence of P200 pemphigoid, which appears to be considerably more frequent than epidermolysis bullosa acquisita.
Fabienne Jouen   +7 more
wiley   +1 more source

An Early Supported Discharge (ESD) Model of Care for Older Adults Admitted to Hospital: A Descriptive Cohort Study

open access: yesClinical Interventions in Aging
Susan Williams,1 Aoife Whiston,2 Ann-Marie Morrissey,1 Clíona O’Riordan,1 Margaret O’Connor,3 Deirdre Hartigan,1 Collette Devlin,1 Rose Galvin1 1School of Allied Health, Faculty of Education and Health Sciences, Ageing Research Centre, Health Research ...
Williams S   +7 more
doaj  

Design and optimisation of rapid real‐time PCR assays for the detection of key Culicoides species

open access: yesMedical and Veterinary Entomology, EarlyView.
Species‐specific real‐time PCR assays were designed and optimised using primer/probe sets targeting C. obsoletus, C. scoticus, C. chiopterus, C. dewulfi, C. pulicaris, C. punctatus and C. impunctatus. Primer specificity and amplification efficiency were validated through in silico specificity analysis and real‐time PCR amplification profiling.
Elsie Isiye   +10 more
wiley   +1 more source

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