Results 61 to 70 of about 5,079 (265)

A cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a

open access: yesScientific Reports, 2017
There is an enormous need to make better use of the ever increasing wealth of publicly available genomic information and to utilize the tremendous progress in computational approaches in the life sciences.
A. C. Aschenbrenner   +8 more
doaj   +1 more source

Toward Predictable Nanomedicine: Current Forecasting Frameworks for Nanoparticle–Biology Interactions

open access: yesAdvanced Intelligent Discovery, EarlyView.
Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova   +4 more
wiley   +1 more source

Les mèmes internet comme pratiques discursives : entre humour, haine et construction identitaire

open access: yesLimes
L’objectif de l’étude est d’examiner comment des mèmes, employés par des internautes marocains et algériens, participent à la diffusion de discours de haine et au durcissement des frontières identitaires en contexte de tensions.
Salaheddine BELARBI
doaj   +1 more source

Optoribogenetic control of regulatory RNA molecules

open access: yesNature Communications, 2020
Short hairpin RNAs can be used to modulate and regulate gene expression. Here the authors generate chimeric RNAs that interact with the photoreceptor PAL, allowing for optoribogenetic control of cell physiology.
Sebastian Pilsl   +4 more
doaj   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

La rhétorique de la beauté : argumentation et discours publicitaires dans la vente des cosmétiques

open access: yesLimes
L’objectif de cette étude est d’analyser les différentes dimensions et fonctions de la rhétorique, en particulier ses composantes (logos, pathos, ethos), ses évolutions et son rôle dans la persuasion, notamment dans le discours publicitaire français.
Maria KONTOZOGLOU
doaj   +1 more source

Explainable AI‐Driven Optimization of Electrode Activation Reduces Power Consumption While Preserving Object Recognition in Retinal Prostheses

open access: yesAdvanced Intelligent Systems, EarlyView.
Explainable artificial intelligence (XAI) guides selective electrode activation in retinal prostheses by emphasizing visually informative regions. XAI‐assisted phosphene generation maintains object recognition performance while significantly reducing stimulation power.
Sein Kim, Hamin Shim, Maesoon Im
wiley   +1 more source

Aspects pragmatiques du proverbe dans le discours électoral : enjeux et dynamiques discursifs

open access: yesLimes
Lors de la campagne électorale régionale (2015) et législative (2016), nous avons noté une récurrence marquée de nombreux proverbes. Cette observation a suscité une réflexion approfondie quant au rôle du proverbe en tant qu'argument d'autorité ...
Badreddine EL-KACIMI
doaj   +1 more source

Shapley Additive Explanation for Local Class Differentiation: Local Explainability for Class Differentiation in Classification Models

open access: yesAdvanced Intelligent Systems, EarlyView.
An instance‐level, model‐agnostic explanation of class differentiation is introduced through SHAP‐LCD, linking probability shifts to feature‐wise Shapley contributions. The method operates on tabular and image data and is released in a fully reproducible implementation, offering a transparent way to examine, at each instance, why predictive models ...
Roxana M. Romero Luna   +2 more
wiley   +1 more source

La contingence du pouvoir discursif

open access: yesLimes
L’article a pour objectif d’analyser la structure logique du pouvoir discursif en le caractérisant par l’accomplissement d’actes de discours. Deux modes différents du pouvoir discursif sont distingués : un mode illocutoire structurel et un mode ...
Gilles GAUTHIER
doaj   +1 more source

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