Results 181 to 190 of about 3,248,997 (314)

Limit theorems for multipower variation in the presence of jumps [PDF]

open access: yes
In this paper we provide a systematic study of the robustness of probability limits and central limit theory for realised multipower variation when we add finite activity and infinite activity jump processes to an underlying Brownian semimartingale ...
Matthias Winkel   +2 more
core  

A topological characterization of stabilizing consensus. [PDF]

open access: yesDistrib Comput
Schmid U, Felber S, Rincon Galeana H.
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

On the existence and the number of limit cycles in evolutionary games

open access: yes
In this paper it is shown that an extended evolutionary system proposed by Hofbauer and Sigmund (1998) may be transformed into a Kukles system. Then a Dulac-Cherkas function related to the Kukles system is derived, which allows us to determine the number
Araujo, Ricardo Azevedo   +1 more
core  

Limit Theorems for Reinforced Jump Processes on Regular Trees [PDF]

open access: yes
Consider a vertex-reinforced jump process defined on a regular tree, where each vertex has exactly b children, with b >= 3. We prove the strong law of large numbers and the central limit theorem for the distance of the process from the root.
Andrea Collevecchio
core  

Ground State Energy Fluctuations of Pinned Elastic Manifolds. [PDF]

open access: yesJ Stat Phys
Fyodorov YV   +2 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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