This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A New Insight into the Threshold and Oscillatory Regimes in Plant-Pathogen Models: A Nutrient-Driven Approach. [PDF]
Damay DP, Peace A.
europepmc +1 more source
Monthly out-of-pocket caps substantially increase actuarial value for high-deductible health plans: a simulation study. [PDF]
Anderson DM, Shafer PR.
europepmc +1 more source
Reported Availability, Additional Cost and Use of Methods to Limit Cross-Contact of Gluten-Free Foods in Restaurants in a Canadian Large Urban Centre. [PDF]
Defries D +4 more
europepmc +1 more source
A Scoping Review and Risk Assessment of Aflatoxin B1 Contamination in Rice, Maize, and Peanut-Based Products Across Selected ASEAN Countries. [PDF]
Ab Dullah SS +6 more
europepmc +1 more source
On Ergodic and Inverse Shadowing Properties of Set-Valued Mapping. [PDF]
Wattan Kamil F, Al-Shara'a IMT.
europepmc +1 more source
Cross-sectional comparisons of different approaches to measuring composite health scores in rural US adults: the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) 2018 Cancer Prevention Recommendations Adherence Score. [PDF]
Hanson KL +4 more
europepmc +1 more source
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The limitations of limitations
IEEE Intelligent Systems, 2003The authors consider human-centered computing, and argue that human factors and applied cognitive psychologists have not just been selective in regarding certain human characteristics as limitations, but have also selected the wrong things and for the wrong reasons.
Flach, John M., Hoffman, Robert R.
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