Results 51 to 60 of about 3,248,997 (314)
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
Central limit theorems for multicolor urns with dominated colors [PDF]
An urn contains balls of d≥2 colors. At each time n≥1, a ball is drawn and then replaced together with a random number of balls of the same color. Let A n = diag (An,1,…,An,d) be the n-th reinforce matrix. Assuming that EAn,j=EAn,1 for all n and j, a few
L. Pratelli +7 more
core +1 more source
This paper describes experiencing the state of transitional awareness that facilitates the ongoing psychotherapy process within borderline states of concern.
Rudolph Bauer
doaj +1 more source
Confidence limits and the limits of confidence [PDF]
Someone once said that what goes up, must come down, but this never seems to be the case with workload. While most busy clinicians have been doing their best to keep their heads above water, others have been temporarily distracted by the many column inches devoted to whether or not Evidence‐Based Medicine represents a new paradigm for their clinical ...
openaire +3 more sources
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker +11 more
wiley +1 more source
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
AbstractOptimization is about finding the best available object with respect to an objective function. Mathematics and quantitative sciences have been highly successful in formulating problems as optimization problems, and constructing clever processes that find optimal objects from sets of objects.
Cesare Carissimo, Marcin Korecki
openaire +3 more sources
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source

