Results 121 to 130 of about 26,438,084 (288)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Structure parameter optimization and bearing limit analysis of the expansion unit of three-roller tube expander. [PDF]
R Soc Open Sci, 2020 Bi G, Qu Z, Wang Z, Dou L, Li M.
europepmc +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Face stability of shield-driven tunnels using multi-tangent technique
Yantu gongcheng xuebaoTo address the face stability problem of deep-buried tunnels under nonlinear conditions, using Power-Law (P-L) criterion the approximate piecewise and by multi-tangent technique, a novel multi-cone failure mechanism is developed for tunnel faces based on
ZHONG Junhao1, 2 , CHIAN Siau Chen2, LI Yongxin3, LIU Mingfang4, CHEN Minghui4, WU Zhenyuan4, LONG Guihua4, YANG Xiaoli1, ZHOU De1
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
High-Frequency Principal Components and Evolution of Liquidity in a Limit Order Market [PDF]
The paper applies a popular methodology of competing risks to the analysis of the timing and interaction between the Deutsche Mark/U.S. dollar transactions, quotes, and cancellations in the Reuters D2000-2 electronic brokerage system.
Konstantin Tyurin
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Critical Height Analysis for Bedding Rock Slopes Using the Upper bound Method of Limit Analysis
工程科学与技术, 2007 :The critical height of bedding rock slope is investigated using the kinematic approach of limit analysis. Firstly, linear equations are introduced to express the shear strength of layered rocks, which is treated as a transverse isotropy material.
doaj