Results 41 to 50 of about 63,374 (271)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Dynamical Behavior and Stability Analysis in a Hybrid Epidemiological-Economic Model with Incubation
Abstract and Applied Analysis, 2014 A hybrid SIR vector disease model with incubation is established, where susceptible host population satisfies the logistic equation and the recovered host individuals are commercially harvested.
Chao Liu, Wenquan Yue, Peiyong Liu
doaj +1 more source
Applied Sciences, 2020 This study numerically analyzes and investigates the effects of the bearing design parameters of a tilting pad journal bearing (TPJB) on the pad-pivot friction-induced nonlinear rotordynamic phenomena and bifurcations.
Sitae Kim, Sangwon Byun, Junho Suh
doaj +1 more source
Macroscopic limit cycle via pure noise-induced phase transition
, 2003 Bistability generated via a pure noise-induced phase transition is reexamined from the view of bifurcations in macroscopic cumulant dynamics. It allows an analytical study of the phase diagram in more general cases than previous methods.
C. Van den Broeck +5 more
core +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Bifurcation-based parameter tuning in a model of the GnRH pulse and surge generator [PDF]
, 2008 We investigate a model of the GnRH pulse and surge generator, with the definite aim of constraining the model GnRH output with respect to a physiologically relevant list of specifications. The alternating pulse and surge pattern of secretion results from
Alexandre Vidal +3 more
core +5 more sources
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
Thermo-diffusive Darcy flow induced by a concentrated source
Ain Shams Engineering Journal, 2016 An analytic study is made of Soret-induced double diffusive Darcy flow produced in an unbounded homogeneous porous medium of uniform porosity and low permeability when a concentrated source embedded instantaneously in the medium starts liberating heat ...
R. Ganapathy, A. Mohan
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Delay-induced multistability near a global bifurcation
, 2007 We study the effect of a time-delayed feedback within a generic model for a saddle-node bifurcation on a limit cycle. Without delay the only attractor below this global bifurcation is a stable node.
E. SCHÖLL +5 more
core +1 more source