Results 141 to 150 of about 2,451,911 (303)

Highly Sensitive Detection of Chymotrypsin Using Gold Nanoclusters with Peptide Sensors

Micromachines
Pancreatic function tests are used to determine the presence of chronic pancreatitis, particularly in the early stage of the disease. Chymotrypsin is an indicator of pancreatic function and is thus related to pancreatic diseases.
Siyuan Zhou, Cheng Liu, Haixia Shi, Li Gao   +3 more
doaj   +1 more source

Quantum Limits of Covert Target Detection

Physical Review Letters
20 pages, 5 ...
Guo Yao Tham, Ranjith Nair, Mile Gu
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Development and Validation of Novel HPLC Methods for Quantitative Determination of Vitamin D3 in Tablet Dosage Form

Pharmaceuticals
In the present work, an efficient isocratic HPLC method was developed for the precise and accurate estimation of vitamin D3 in tablet form. The chromatographic conditions comprised an L3 silica column (5 µm in particle size, 4.6 mm × 250 mm) with a ...
Muhammad Saqib Gohar, Taj Ur Rahman, Ali Bahadur, Ashraf Ali, Sarah Alharthi, Nora Hamad Al-Shaalan   +5 more
doaj   +1 more source

relative detection limit [PDF]

, 2014
Citation: 'relative detection limit' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.R05263 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for
openaire   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Novel Detection of Enterococcus faecalis Using Multiple Cross Displacement Amplification Linked with Gold Nanoparticle Lateral Flow Biosensor

Infection and Drug Resistance, 2019
Xu Chen,1,2 Kai Ma,3 Xu Yi,1 Ziyu Xiao,4 Lijuan Xiong,3 Yu Wang,5 Shijun Li2 1Central Laboratory of the Second Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou 550003, People’s Republic of China; 2Laboratory
Chen X, Ma K, Yi X, Xiao Z, Xiong L, Wang Y, Li S   +6 more
doaj  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Comparison of Minimum Detectable Concentration with the IUPAC Detection Limit

Measurement Science Review, 2008
Janiga I., Mocak J., Garaj I.
doaj   +1 more source

Evaluation of the Limit of Detection of Bacteria by Tandem Mass Spectrometry Proteotyping and Phylopeptidomics. [PDF]

Microorganisms, 2023
Mappa C, Alpha-Bazin B, Pible O, Armengaud J.   +3 more
europepmc   +1 more source