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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
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Evaluation of detection limit estimators
Chemometrics and Intelligent Laboratory Systems, 1988Abstract A large number of definitions, formulae, and experimental procedures have been developed for estimating the minimum detectable level of a measurement process. These definitions vary according to the intended purpose of the estimator, while the formulae vary according to the mathematical approach and statistical model assumed.
Forest C. Garner, Gary L. Robertson
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Limits for the Detection of Binaural Beats
The Journal of the Acoustical Society of America, 1969This study investigates the probability of detecting binaural beats as a function of the frequency of the standard signal used (f1) and of the dichotic frequency difference (|f1−f2|). The present findings indicate that the upper frequency limit for the perception of binaural beats depends upon the dichotic frequency differences employed, the ...
D R, Perrott, M A, Nelson
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Limiting Factors for the Detection of Orientation
Perception, 1998First steps of visual-information processing in primates are characterised by a highly ordered representation of the outside world on the cortex. Two prominent features of cortical organisation are the retinotopic mapping of position in the visual field on the first stages of the visual stream, and the systematic variation of orientation preference in
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Limitations in Improving Detection of Pancreatic Adenocarcinoma
Future Oncology, 2009To review the current trends in pancreatic cancer research and propose alternatives for an earlier diagnosis.A search was conducted using the PubMed and Scielo electronic databases to find statistics related to the incidence of pancreatic cancer.Pancreatic cancer is the fourth most common cause of cancer mortality in the USA; in Colombia the incidence ...
Mendieta Zerón, Hugo +2 more
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Residue analytical limit of detectability
1965Determining how small an amount of a given pesticide or drug can be detected in plant or animal tissue has a profound effect on the commercialization of the compound being investigated. This effect lies within the complexities of governmental administration of pesticide and drug regulations, and is not a subject of this discussion.
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Detection Limit of Isotope Dilution Mass Spectrometry
Analytical Chemistry, 2002The detection limit is an important figure of merit for evaluating instrumentation and analytical methods. While the detection limit for techniques using linear calibration functions has been studied extensively, this fundamental metric has rarely been discussed for mass spectrometry that bases the calibration on the principle of isotope dilution.
Lee L, Yu +2 more
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Limit of blank, limit of detection and limit of quantitation.
The Clinical biochemist. Reviews, 2010* Limit of Blank (LoB), Limit of Detection (LoD), and Limit of Quantitation (LoQ) are terms used to describe the smallest concentration of a measurand that can be reliably measured by an analytical procedure. * LoB is the highest apparent analyte concentration expected to be found when replicates of a blank sample containing no analyte are tested. LoB =
David A, Armbruster, Terry, Pry
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The Joint Consequence of Detection Limit Censoring and Detection Limit Determination Uncertainty
Journal of Testing and EvaluationABSTRACT Method detection limits estimated from specialized data studies are frequently used as a basis for left censoring reported data. Estimated method detection limits are frequently impacted by the failure to fully mimic all measurement system characteristics represented in process quality data collection.
Thomas J. Bzik, Suhas N. Ketkar
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