Results 101 to 110 of about 166,185,938 (258)

Systematic Position Mapping of Split CRISPR‐Cas12a Activators Enables Highly Sensitive miRNA Detection and Cancer Cell Stratification

Advanced Science, EarlyView.
ABSTRACT Amplification‐free Cas12a diagnostics with split crRNA enable rapid and programmable target recognition, yet insufficient understanding of DNA activator architecture prevents predictable control over trans‐cleavage activity and sensitivity. Here we systematically map over 200 split DNA activator configurations by introducing nicks at every ...
Xiaoyan Tang, Zhe Li, Yuning Lu, Miao Ma, Zijian Mo, Jiajun Ke, Xinyu Luan, Tiangang Luan, Junqiu Zhai   +8 more
wiley   +1 more source

Retention time, recovery efficiency (n = 10), limit of detection (LOD), and limit of quantification (LOQ) for DMAP and six chlorinated NNs in the urine.

, 2015
aN-desmethyl-acetamipridRetention time, recovery efficiency (n = 10), limit of detection (LOD), and limit of quantification (LOQ) for DMAP and six chlorinated NNs in the urine.
Jemima Tiwaa Marfo (821931), Hazuki Mizukawa (821933), Shouta M. M. Nakayama (821932), Kumiko Taira (483174), Yoshinori Ikenaka (464562), Yoshiko Aoyama (483176), Mayumi Ishizuka (264469), Kazutoshi Fujioka (483175)   +7 more
core   +1 more source

Light-Triggered Graphene/Black Phosphorus Heterostructure FET Platform for Ultrasensitive Detection of Alzheimer’s Disease Biomarkers at the Zeptomole Level

Research
Due to the low concentration of amyloid-beta (Aβ) in plasma and the high content of interfering factors, the conventional detection method for the quantification of Aβ still faces the problem of insufficient limit of detection (LOD).
Huide Wang, Meng Qiu, Chen Wang, Liding Zhang, Ning Fan, Zhi Chen, Yi Liu, Tianzhong Li, Ziqian Wang, Yihan Zhu, Yule Zhang, Xilin Tian, Yun Wang, Mingmin Yang, Dianyuan Fan, Qingming Luo, Ke Jiang, Haiming Luo, Han Zhang   +18 more
doaj   +1 more source

Validation of a Thin-Layer Chromatography for the Determination of Hydrocortisone Acetate and Lidocaine in a Pharmaceutical Preparation

The Scientific World Journal, 2014
A new specific, precise, accurate, and robust TLC-densitometry has been developed for the simultaneous determination of hydrocortisone acetate and lidocaine hydrochloride in combined pharmaceutical formulation.
Małgorzata Dołowy, Katarzyna Kulpińska-Kucia, Alina Pyka   +2 more
doaj   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

The limit of detection (LOD), limit of quantification (LOQ), detection frequency (DF) and geometric mean (GM), geometric standard deviation (GSD) and median of analyzed PBDEs in eight brands of bovine milk samples analyzed in triplicate.

, 2017
The limit of detection (LOD), limit of quantification (LOQ), detection frequency (DF) and geometric mean (GM), geometric standard deviation (GSD) and median of analyzed PBDEs in eight brands of bovine milk samples analyzed in triplicate.
Xiaopeng Chen (2010004), Katherine Dang (3639217), Yanping Lin (3639220), Birgit Puschner (384904)   +3 more
core   +1 more source

Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform Toward Non‐Invasive Diagnostics

Advanced Science, EarlyView.
Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform toward Non‐Invasive Diagnostics is a nature‐inspired strategy that engineers controlled randomness within block copolymer lamellae to achieve optical isotropy without compromising nanoscale periodicity.
Jin Man Kim, Wonsik Kim, Wansun Kim, Yeon‐Hee Kim, Samjin Choi, Jang Hwan Kim, Hyeong Min Jin   +6 more
wiley   +1 more source

The limit of detection (LOD), limit of quantification (LOQ), detection frequency (DF) and geometric mean (GM), geometric standard deviation (GSD) and median concentrations (pg/mL) of analyzed PCBs in eight brands of bovine milk samples analyzed in triplicate.

, 2017
The limit of detection (LOD), limit of quantification (LOQ), detection frequency (DF) and geometric mean (GM), geometric standard deviation (GSD) and median concentrations (pg/mL) of analyzed PCBs in eight brands of bovine milk samples analyzed in ...
Xiaopeng Chen (2010004), Katherine Dang (3639217), Yanping Lin (3639220), Birgit Puschner (384904)   +3 more
core   +1 more source

Carbon dots: Review of recent applications and perspectives in bio-sensing and biomarker detection

Sensing and Bio-Sensing Research
Carbon Dots (CDs) are carbon-based nanoparticles with relatively strong and tunable fluorescence emission properties and relatively good photo stability, which are increasingly used in sensing and biosensing as reported in hundreds of research ...
Xeniya Terzapulo, Aiym Kassenova, Alissa Loskutova, Rostislav Bukasov   +3 more
doaj   +1 more source

Renal Clearable Luminogenic Reporter for Ultrasensitive Influenza Virus Imaging and Efficient Antiviral Therapies Monitoring in Living Mice

Advanced Science, EarlyView.
A viral luminogenic reporter with chemiluminescence/fluorescence dual‐response and efficient renal clearance was developed for non‐invasive imaging and urinalysis of H1N1 virus protease, allowing for remote detection of H1N1 virus infections and monitoring of antiviral therapeutic efficacy in living mice.
Bankang Ruan, Chudan Liang, Meilin Hu, Weiping Xu, Jingjing Che, Jun Qian, Bingcai Jiang, Linna Liu, Xiancai Ma, Jiaguo Huang   +9 more
wiley   +1 more source