Results 91 to 100 of about 31,974 (218)

Chemical Ionization Mass Spectrometry: Fundamental Principles, Diverse Applications, and the Latest Technological Frontiers

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The review examines the evolution of chemical ionization mass spectrometry (CI‐MS), a technique developed in 1966 by Field and Munson. CI is a soft‐ionization method that produces more intense molecular ions with less fragmentation than electron ionization (EI).
Malvika Dutt, Adriana Arigò, Giorgio Famiglini, Pierangela Palma, Achille Cappiello   +4 more
wiley   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Direct Electrochemical Detection of Tyramine in Beer Samples Using a MWCNTs Modified GCE

Sensors
In this study, an electrochemical method is presented for the direct determination of tyramine in beer samples. A multi-walled carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE) was developed for the detection and quantification of tyramine
Cláudio M. R. Almeida, Maria Fátima Barroso, Manuela M. Moreira, Júlia M. C. S. Magalhães, Luisa Durães   +4 more
doaj   +1 more source

Synthesis and application of alginate@CuFe2O4 polymeric spheres in 17‐β‐estradiol adsorption processes in Amazonian rivers

Polymer International, EarlyView.
Magnetic alginate beads, functionalized with copper ferrite, effectively remove 17‐β‐estradiol from Amazonian water, exhibiting optimized 238.65 μg g−1 capacity, fast 40 min kinetics, easy recovery, and successful remediation. Abstract The presence of endocrine‐disrupting compounds, such as 17‐β‐estradiol, in aquatic ecosystems poses a significant ...
Dante S Silva, Adriano R. S Silva, Yasmin S Medeiros, José R Santos Neto, Jamily L dos Santos, Ananias L dos Santos, Roberta L. S Bernardino, Giulian César S Sá, Leandro A Pocrifka, Sidnei C dos Santos, Emilly C Silva   +10 more
wiley   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Abundance of atrazine degrading genes trzN versus atzA in soil cultures and in situ degradation rates

Pest Management Science, EarlyView.
Atrazine degradation in agricultural soils showed in situ half‐lives of 36–225 days. Field and laboratory results indicate active microbial hydrolysis driven mainly by trzN. Biphasic degradation sustains long‐term persistence, maintaining the potential for groundwater contamination despite reduced immediate leaching risk.
Truphena Akinyi, Damiana Diaz‐Reck, Aman Raj, Anat Bernstein   +3 more
wiley   +1 more source

Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 540-550, March 2025.
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou, Anne Auperin, Jôel Guigay, Sébastien Salas, Sebastien Benzekry   +4 more
wiley   +1 more source

Laser‐Assisted In Situ Fabrication of rGO/Bi2O3 Nanocomposites for Heavy Metal Sensing

Small, EarlyView.
Rapid CO2 laser irradiation drives the in situ formation of Bi2O3 nanoplatelets within reduced graphene oxide, yielding flexible, reproducible electrodes with excellent stripping voltammetric performance toward trace heavy metals. ABSTRACT In this work, we introduce a laser‐assisted approach to synthesize reduced graphene oxide/bismuth oxide (III) (rGO/
Andy Bruno, Ana Ameda, Ivan Dědek, Majlinda Vasjari, Michal Otyepka, Ruslán Alvarez‐Diduk, Arben Merkoçi   +6 more
wiley   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, EarlyView.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

Bisphenols and Phthalates in Bottled Mineral Water: First Evidence of Co‐Occurrence, Estrogenic Activity, and Health Risk in Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), its structural analogs, and phthalates are synthetic chemicals widely used, with documented endocrine‐disrupting activity. This study aimed to develop and validate a selective multiresidue analytical method for the simultaneous determination of BPA, 10 bisphenol analogs, and six phthalates in PET‐bottled mineral water.
Giulia Boito Reyes, Lucas Correia Gonçalves, Fernanda Cristina Iba Molinari, José Eduardo Gonçalves   +3 more
wiley   +1 more source