Results 181 to 190 of about 31,974 (218)

Systematic Optimization of an SLE‐DAPTAD LC–MS/MS Workflow for Simultaneous Quantification of Low‐Abundance Vitamin D3 Metabolites in Plasma

Rapid Communications in Mass Spectrometry, Volume 40, Issue 20, 30 October 2026.
ABSTRACT Rationale Liquid chromatography–tandem mass spectrometry (LC–MS/MS) analysis of vitamin D3 metabolites is analytically challenging because these compounds are structurally similar, strongly matrix‐associated, and have poor ionization efficiency.
Marzieh Amirmostofian, Michael D. Wiese, Paul H. Anderson, Peter Hoffmann   +3 more
wiley   +1 more source

Lack of confirmatory data following Article 12 MRL reviews for dicloran, fenazaquin and tebufenozide. [PDF]

EFSA J
European Food Safety Authority (EFSA).
europepmc   +1 more source

A Rapid and Sensitive LC–MS/MS Method for Quantification of NDSRI in Melatonin Drug Product via Controlled In Situ Formation

Biomedical Chromatography, Volume 40, Issue 10, October 2026.
ABSTRACT Nitrosamine drug substance–related impurities (NDSRIs) pose a significant safety risk due to their mutagenic and carcinogenic potential, prompting strict regulatory oversight under ICH M7. The propensity for in situ formation of NDSRIs during analytical procedures, particularly in active pharmaceutical ingredients containing reactive amines ...
Jaya Yalamanchili, Ganja Himavathi, Salakolusu Suresh   +2 more
wiley   +1 more source

Analytical Validation of NETest2.0^®, a Novel Multigene Blood-Based Molecular Assay for Neuroendocrine Tumors. [PDF]

Cancers (Basel)
Kidd M, Koduru SV, Halim A.
europepmc   +1 more source

Quantification of Sulfonated Polyacrylamides by SEC‐UV in Produced Water: Validation and Oilfield Case Study

Journal of Applied Polymer Science, Volume 143, Issue 33, September 5, 2026.
Size exclusion chromatography with UV–vis detection, combined with ultrasonication pretreatment, enables sensitive detection and quantification of back‐produced polymer at very low concentrations in produced water. This approach supports reliable polymer monitoring and offers a practical route to improve surveillance of polymer flooding performance ...
Eduardo José Creatto, Luis Maqueira, Daniel da Silva Vicente, Thierry Leblanc, Nathaniel Terra, Lara Arinelli, Aurora Pérez‐Gramatges   +6 more
wiley   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

Global Regulatory Mandates as Drivers for Advanced Chemical Analysis in Food Safety. [PDF]

Foods
Guo L, Dong X, Zhou H, Liu Z, Xiong X.
europepmc   +1 more source

Mineral profile of cocoa powder: Analytical approach in commercial samples

Journal of the Science of Food and Agriculture, Volume 106, Issue 12, Page 7056-7065, September 2026.
Abstract BACKGROUND Cocoa powder is widely used in the food industry and has high nutritional value due to its composition, including minerals. The main factors related to the presence of minerals in cocoa powder are soil, processing, and cultivation practices.
Mateus Barbosa Silva, Herick Macedo Santos, Joane Cristina Costa Pereira, Heliara Caires Sousa, Raildo Mota de Jesus, Danilo Junqueira Leão, Leandro Soares Santos, Sibelli Passini Barbosa Ferrão   +7 more
wiley   +1 more source

Machine learning prediction and calibration of cellulose-based solid-phase extraction performance for pharmaceuticals across aqueous matrices. [PDF]

RSC Adv
Akor E, Olorunnisola D, Alfred MO, Ejeromedoghene O, Omorogie MO.   +4 more
europepmc   +1 more source

Validation of a Graphite Furnace Atomic Absorption Spectrometry (GFAAS) Method for Determining Total Antimony in Organs of Mice. [PDF]

ACS Omega
Coelho LD, Souza MMD, Paiva MJN, Nascentes CC, Oliveira MC, Aguiar MMG.   +5 more
europepmc   +1 more source