Results 61 to 70 of about 31,974 (218)

A validated RP-HPLC method for quantitative determination of sodium taurocholate in bovine bile extract [PDF]

Pharmacia
Sodium taurocholate, a major component of bile salts, plays an important role in pharmaceutical and biochemical applications. This study aimed to develop and validate a high-performance liquid chromatography (HPLC) method for accurately determining ...
Betania Sitepu, Amirah Adlia, Lucy Sasongko   +2 more
doaj   +3 more sources

Micro‐QuEChERS Extraction for Broad‐Spectrum LC‐QQQ‐MS Quantification of Nitazene Analogs in Plasma: A Validated Method With Casework Application

Drug Testing and Analysis, EarlyView.
Micro‐QuEChERS sample preparation coupled to LC‐QQQ‐MS enabled sensitive quantification of nitazene analogs in 100 μL of plasma. The validated method provided low detection limits and was successfully applied to an authentic intoxication case involving N‐pyrrolidino protonitazene, supporting clinical and forensic toxicology workflows.
Karla A. O. Souza, Náthaly C. B. F. Santos, Rafael Lanaro, Sara E. Walton, Alex J. Krotulski, Barry K. Logan, Mauricio Yonamine, Jose Luiz Costa   +7 more
wiley   +1 more source

Development and Validation of a Method for the Analysis of Multiple Pesticides in Fishery Products Using Gas Chromatography with Micro-Electron Capture Detection and Gas Chromatography–Tandem Mass Spectrometry

Separations
This study aims to develop a simultaneous analytical method for detecting 19 pesticides, including 4,4′-DDD, in fishery products using gas chromatography with micro-electron capture detection (GC-μECD) and gas chromatography–tandem mass spectrometry (GC ...
Myungheon Kim, Mihyun Cho, Changkyo Seo, Jaebin Im, Changhyeon Park, Yoonmi Lee, Mi-Ra Jo, Yong-Sun Moon, Moo-Hyeog Im   +8 more
doaj   +1 more source

Determination of benzimidazole residues and their metabolites in raw milk using high performance liquid chromatography-diode array detection

Mljekarstvo, 2017
A new analytical method using high performance liquid chromatography-diode array detector (HPLC-DAD) was developed for the analysis of 18 benzimidazoles and their metabolites in milk.
Marija Denžić Lugomer, Damir Pavliček, Nina Bilandžić, Darko Majnarić   +3 more
doaj   +1 more source

Antidepressant Misuse in Esports: A Review of Pharmacology, Adverse Effects, Pharmacokinetics and Biomatrix‐Based Detection for Anti‐Doping Applications

Drug Testing and Analysis, EarlyView.
This review highlights the misuse of antidepressants as potential cognitive‐enhancing agents in Esports. Despite pharmacological effects that overlap with those of psychostimulants, antidepressants remain an under‐recognised source of doping in Esports.
Kassim Ali Salum, Shao‐Hsin Hung, Meng‐Tsang Hsieh, Mei‐Chich Hsu, William Chih‐Wei Chang   +4 more
wiley   +1 more source

Detection, Isolation and Characterization of Principal Synthetic Route Indicative Impurity in Lansoprazole

E-Journal of Chemistry, 2010
An unknown impurity in lansoprazole (2-[[[3-methyl-4-(2, 2, 2-trifluoroethoxy)-2-pyridyl] methyl] sulfinyl] benzimidazole) was detected by HPLC and was identified as des-(trifluoroethoxy) lansoprazole, an principal synthetic route indicative impurity of ...
K. S. V Srinivas, K. Mukkanti, R. Buchi Reddy, P. Srinivasulu   +3 more
doaj   +1 more source

Toxicokinetic Study of a Gastroprotective Dose of Capsaicin by HPLC-FLD Method

Molecules, 2019
Background: A low dose of capsaicin and its natural homologs and analogs (capsaicinoids) have shown to prevent development of gastric mucosal damage of alcohol and non-steroid anti-inflammatory drugs.
Mónika Kuzma, Krisztina Fodor, Attila Almási, Gyula Mózsik, Tibor Past, Pál Perjési   +5 more
doaj   +1 more source

Machine Learning–Enhanced Fluorescence Cryptography with NADH‐Responsive Polymer Dots

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This study presents a smart anticounterfeiting system using semiconducting polymer dots (Pdots) that exhibit tunable fluorescence responses to NADH. By integrating these dynamic optical signals with machine learning–based decoding, the work establishes a secure and intelligent encryption platform, showing a novel strategy that links chemical sensing ...
Zhengkun Zhan, Mingyue Gong, Zirui Zeng, Hangyu Liu, Xiaoliang Li, Zhuxin Dong, Xiaoju Men, Haobin Chen   +7 more
wiley   +1 more source

High‐Throughput Multi‐Capillary Electrophoresis

ELECTROPHORESIS, EarlyView.
Multi‐capillary electrophoresis enables high‐throughput pharmaceutical analysis through simultaneous multi‐capillary operation, achieving a five‐fold reduction in run time per sample with improved sensitivity and linearity. Method transfer from single‐capillary systems is straightforward, supporting rapid and accurate quantification across diverse ...
Jana Drewes, Sarah Meyer, Isobel Roberts, Cleo Fanny, Philip A. Doble, Dayanne Mozaner Bordin, Janice I. McCauley   +6 more
wiley   +1 more source

By‐product of heparin extraction as a sustainable alternative to enhance the use of nitrogen in agriculture

Environmental Progress &Sustainable Energy, EarlyView.
Abstract This study evaluates the potential of a new organic fertilizer derived from porcine intestinal mucosa (designated BHE), a by‐product of the heparin extraction process, as a sustainable nitrogen (N) source for agriculture. The work was conducted in two stages: (i) chemical and spectroscopic characterization of BHE compared with poultry litter ...
Aline Zanquetti, Felipe Augusto Bueno Rossi, Jonatas Thiago Piva, Larissa Macedo dos Santos‐Tonial   +3 more
wiley   +1 more source