Results 101 to 110 of about 4,868,976 (301)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Order Submission: The Choice between Limit and Market Orders [PDF]
Most financial markets allow investors to submit both limit and market orders, but it is not always clear what affects the choice of order type. The authors empirically investigate how the time between order submissions, changes in the state of the order
Stephen G. Sapp, Ingrid Lo
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Clearing the Air on the Debt Limit [PDF]
, 2017 This report provides clarifications on five common debt limit contentions or questions which are: The United States had debt limits before 1917, Did the Federal government default in the 1970s?, Were "clean" debt limit increases once the norm?, Could a ...
Austin, D. Andrew, Thomas, Kenneth R.
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
The concept of finite limit of a function at one point as explained by students of non-compulsory secondary education [PDF]
, 2012 We review various educational studies of the mathematical concept of limit of a function at a point that indicate how colloquial uses of the terms “to approach,” “to tend toward,” “to reach,” “to exceed” and “limit” influence students’ conceptions of ...
Ruiz Hidalgo, Juan Francisco +5 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Cancellation and Uncertainty Aversion on Limit Order Books [PDF]
This paper models limit order books where each trader is uncertain of the underlying distribution in the asset's value to others. If this uncertainty is rapidly resolved, eeting limit orders are submitted and quickly cancelled.
Jeremy Large
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Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Teologická ReflexeThe works of Josephus (37 – ca. 100 CE) have been extensively cited ever since he wrote them. Strangely enough, however, hardly any of his many users, prior to the 1980s, asked basic questions about the structures, themes, and audiences of these ...
Steve Mason
doaj +1 more source
Notes for a Contingent Claims Theory of Limit Order Markets [PDF]
This paper provides a road map for building a contingent claims theory of limit order markets grounded in a simple observation: limit orders are equivalent to a portfolio of cash-or-nothing and asset-or-nothing digital options on market order flow ...
Bruce N. Lehmann
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