Results 131 to 140 of about 9,478,616 (387)

Representing the Lived Parents’ Experience of How to Answer the Religious Questions of Their Primary School Children

open access: yesمسائل کاربردی تعلیم و تربیت اسلامی, 2021
Objective: This study aimed to identify how parents can answer to their children’s religious questions. Method: To achieve this objective, the phenomenological method was used.
somayeh Gholami, Mohammad Hosseini
doaj  

Religious Education in the Search for Answers to Existential Human Questions

open access: yesPaedagogia Christiana, 2018
There are various ways in which man tries to reach a satisfactory answer to his questions about where he comes from, what he is aiming at, what the purpose and meaning of his life is. These questions are usually called existential questions.
Zbigniew Marek
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sovereignty over Land and Sea in the Arctic Area

open access: yesAgenda Internacional, 2016
The paper reviews the claims over land and waters in the Arctic area. While almost all the disputes over land have today been settled, several questions relating to law of the sea are still pending.
Tullio Scovazzi
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Život a dílo Josepha Flavia

open access: yesTeologická Reflexe
The works of Josephus (37 – ca. 100 CE) have been extensively cited ever since he wrote them. Strangely enough, however, hardly any of his many users, prior to the 1980s, asked basic questions about the structures, themes, and audiences of these ...
Steve Mason
doaj   +1 more source

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