On the Central Limit Question Under Absolute Regularity
Let \(X=(X_ k,k\in {\mathbb{Z}})\) be a strictly stationary sequence of random variables on a probability space (\(\Omega\),\({\mathfrak F},P)\). Denote \(S_ n=X_ 1+...+X_ n\), \(n=1,2,..\). \(\beta ({\mathfrak A},{\mathfrak B})=\sup \quad 2^{-1}\sum^{I}_{i=1}\sum^{J}_{j=1}| P(A_ i\cap B_ j)- P(A_ i)P(B_ j)|,\) where sup is taken over all pairs of ...
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Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
On the question of limits : The role of ecotones in the management and reintegration of transforming urban environments : Urban ecotones as territorial indicators and interfaces of urban reconfiguration : An applied study of the urban regional mosaic of the city of Thessaloniki, Greece [PDF]
Konstantinos Kourkoutas
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Resolution Limits of Non-Adaptive 20 Questions Search for Multiple Targets [PDF]
Lin Zhou, Lin Bai, Alfred O. Hero
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Several questions and hypotheses concerning the limit polynomials for Chacon transformation [PDF]
A. A. Prikhod’ko, V. V. Ryzhikov
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