Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2015 The aim of this thesis is to explain the legal term "limitations". This work is based on the new Law no. 89/2012 Coll., Civil Code, which has been effective since 2014.The thesis compares the limitation according the new Civil Code with the Law no.
PETŘÍKOVÁ, Kateřina
core
Rv3839-Rv3840 links the endogenous heme biosynthesis pathway with Mycobacterium tuberculosis adaptation to nitric oxide and iron limitation stress. [PDF]
PLoS GenetQuirk NF, Gregory KN, Morita YS, Tan S.
europepmc +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Memorandum: Press Conference Memos, November 7, 1921
, 1921 Press Conference Memoranda, Conference on Limitation of Armament, November 7, 1921 at the State Department, typed, 3 pages.
Tarbell, Ida M.
core
Functional limitations and loneliness in middle-aged and older adults: differentiating emotional loneliness and social loneliness. [PDF]
BMC Public HealthBeller J, Graßhoff J, Sperlich S.
europepmc +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Frequency limitation in calibrating microwave test fixtures
, 2002 The problem of frequency limitation arising in calibration of the test fixtures is investigated in this paper. It is found that at some frequencies periodically, the accuracy of the methods becomes very low, and.
Zhu NH +4 more
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Effects of biologic and targeted synthetic disease modifying antirheumatic drugs (b/tsDMARDs) on patient-reported outcome domains in rheumatoid arthritis: a systematic review and network meta-analyses. [PDF]
RMD Openvan Esveld L +9 more
europepmc +1 more source