Results 141 to 150 of about 322,815 (308)

Fragility of Assumptions: Response. [PDF]

open access: yesOrthop J Sports Med
Chan J   +6 more
europepmc   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

The Many Faces of Indeterminacy in Interactive Deadbots. [PDF]

open access: yesPhilos Technol
Kozlovski A, Harbinja E, Dobbe R.
europepmc   +1 more source

Limitation of shipowners' liability

open access: yes, 1989
Consideration is given firstly to the origins of the principle of a shipowner being entitled to limit his liability to third parties who have suffered loss or injury as a result of the negligent navigation or management of his ship noting that the principle evolved as a matter of public policy designed to encourage shipping and trade.
openaire   +1 more source

Mapping opioid exposure through prescription data and postmortem analysis of opioid drugs in multiple tissues

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins   +23 more
wiley   +1 more source

Practice, knowledge and attitude of physicians and pharmacists towards the spontaneous reporting system of adverse drug reactions in Switzerland

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Introduction Introduction Reporting adverse drug reactions (ADRs) is essential for detecting drug risks. Despite legal obligations in Switzerland, underreporting remains an issue. This study assessed practice, knowledge and attitudes towards the spontaneous ADR reporting system among physicians and pharmacists.
Fiona A. Strobel   +2 more
wiley   +1 more source

Spatial Mapping of Genetic Liability to Psychiatric Disorders in the Adult Human Hippocampus. [PDF]

open access: yesBiol Psychiatry Glob Open Sci
Baran Y   +6 more
europepmc   +1 more source

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