Results 51 to 60 of about 321,015 (291)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Mendelian Randomization and Double Machine Learning Modeling Reveal Brain Imaging‐Derived Phenotypes as Functional Contributors to 18 Autoimmune Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
This schematic integrates the eight statistically significant causal relationships identified between 1,366 brain imaging‐derived phenotypes (IDPs) and 18 autoimmune inflammatory diseases (AIDs). Arrows indicate the direction of causality inferred from bidirectional two‐sample MR analyses.
Jinbin Chen   +8 more
wiley   +1 more source

Opportunities and Challenges of Islamic Republic of Iran’s Accession to the Vienna Convention on Civil Liability for Nuclear Damage [PDF]

open access: yesمجله علوم و فنون هسته‌ای, 2018
Nowadays the Islamic Republic of Iran is known as a nuclear state and It’s nuclear activities are increasing every day. However it has not been thought about liability for potential hazards of these damages.
A Shamshiri, F Amirabadi Farahani
doaj  

CHARAKTER PRAWNY ODPOWIEDZIALNOŚCI ZAWODOWEJ W BUDOWNICTWIE

open access: yesZeszyty Prawnicze, 2016
THE LEGAL NATURE OF PROFESSIONAL LIABILITY IN THE CONSTRUCTION INDUSTRY Summary The article concerns the legal nature of professional liability in the construction industry (Articles 95-101 of Ustawa z dnia 7 lipca 1994 r.
Bartosz Majchrzak
doaj   +1 more source

Limiting audit firms’ liability: A step in the right direction? (Proposals for a new audit liability regime in Europe revisited) [PDF]

open access: yes
This paper considers the responses of six audit firms, to the four options presented by the European Commission in reforming auditors’ liability. Whilst agreeing with a limitation in audit firms’ liability, it does not consider the means of limitation ...
Ojo, Marianne
core   +1 more source

Accountability from the perspective of Malaysian governance [PDF]

open access: yes, 2009
Generally, accountability is often associated with a concept of answerability, responsibility, blameworthiness, liability etc. Commonly, the concept of accountability from the perspective of governance is the means to control the public administration in
A. Kadir, Nadrah   +2 more
core   +1 more source

3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction

open access: yesAdvanced Science, EarlyView.
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley   +1 more source

Pravni učinci primjene ISM kodeksa na ograničenje odgovornosti brodara

open access: yesPoredbeno Pomorsko Pravo, 2001
Opisuju se i analiziraju pravne značajke ISM kodeksa kao konvencijskih međunarodnih pravila o standardu za sigurno upravljanje i vođenje broda i sprječavanje onečišćenja morskog okoliša.
Drago Pavić
doaj  

Agreements on Release of Contractual Liability of Entrepreneurs in Russia and China

open access: yesBRICS Law Journal
This article is devoted to a comparative analysis of the provisions of the civil codes of the Russian Federation and the People’s Republic of China regulating the conclusion of agreements on the release or limitation of civil liability. In the context of
S. Zimneva, Xiao He
doaj   +1 more source

The Individual Limited Liability Company in the Brazilian Legal System and Portuguese Experience of Single Shareholder Private Companies

open access: yesRevista Brasileira de Direito Empresarial, 2016
The scope of this essay is to analyze aspects of individual limited liability company in the Brazilian legal system, which raises the issue of the requirement of minimum capital contribution to the company’s constitution.
Eugênio Duarte Vasques
doaj   +1 more source

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