Results 51 to 60 of about 322,815 (308)

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Civil Procedure and the Ministerial Exception [PDF]

open access: yes, 2017
In Hosanna-Tabor Evangelical Lutheran Church & School v. EEOC, the U.S. Supreme Court recognized a ministerial exception to the ordinary rules of employer liability.
Smith, Peter J., Tuttle, Robert W.
core   +2 more sources

A Metal‐Free Carbon Monoxide Prodrug Suppresses Metastasis of Pancreatic and Breast Cancer

open access: yesAdvanced Science, EarlyView.
A metal‐free carbon monoxide (CO) prodrug, CO‐116, delivers controlled systemic CO without inhalation. CO suppresses the HRG1–heme axis, reducing intracellular heme availability. Attenuation of this pathway inhibits metastatic progression in pancreatic and triple‐negative breast cancer models.
Tiantian Zhang   +15 more
wiley   +1 more source

The Collision of Ships at Sea: Problems of Responsibility and Jurisdiction

open access: yesУправленческое консультирование, 2019
The purpose of this article is to review the main problems of liability and jurisdiction in the collision of ships at sea. The collision of ships is one of the most common accidents at sea, entailing further legal consequences.
N. A. Butakova
doaj   +1 more source

Limiting audit firms’ liability: A step in the right direction? (Proposals for a new audit liability regime in Europe revisited) [PDF]

open access: yes
This paper considers the responses of six audit firms, to the four options presented by the European Commission in reforming auditors’ liability. Whilst agreeing with a limitation in audit firms’ liability, it does not consider the means of limitation ...
Ojo, Marianne
core   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

open access: yesAdvanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun   +5 more
wiley   +1 more source

CHARAKTER PRAWNY ODPOWIEDZIALNOŚCI ZAWODOWEJ W BUDOWNICTWIE

open access: yesZeszyty Prawnicze, 2016
THE LEGAL NATURE OF PROFESSIONAL LIABILITY IN THE CONSTRUCTION INDUSTRY Summary The article concerns the legal nature of professional liability in the construction industry (Articles 95-101 of Ustawa z dnia 7 lipca 1994 r.
Bartosz Majchrzak
doaj   +1 more source

Sound the Alarm: Limitations of Liability in Alarm Service Contracts [PDF]

open access: yes, 2016
Home and business owners increasingly rely on alarm systems to protect against theft and property damage. When a burglary or fire occurs and an alarm service customer discovers that the alarm company negligently failed to call the police or fire ...
Cohen, Joshua N.
core   +1 more source

Polar Lattice‐Distorted Motifs Enable Synergy of Local Polarization/Dipole Fields for Concurrent Glyphosate Wastewater Remediation and CO Evolution

open access: yesAdvanced Science, EarlyView.
Photocatalytic treatment of glyphosate herbicide in agricultural wastewater is achieved through the cooperative effect of the local polarization field and dipole field mediated by lattice‐distorted carbon nitride. Glyphosate is completely degraded via selective C─P bond cleavage with a CO evolution rate of 1166 µmol g−1 h−1.
Daoping Chen   +7 more
wiley   +1 more source

Pravni učinci primjene ISM kodeksa na ograničenje odgovornosti brodara

open access: yesPoredbeno Pomorsko Pravo, 2001
Opisuju se i analiziraju pravne značajke ISM kodeksa kao konvencijskih međunarodnih pravila o standardu za sigurno upravljanje i vođenje broda i sprječavanje onečišćenja morskog okoliša.
Drago Pavić
doaj  

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