Results 101 to 110 of about 99,860 (313)

Distortion in the Communication of Nonsignificant Primary Outcomes: The Spin Strategy in Multiple Sclerosis Trials

open access: yesAnnals of Neurology, EarlyView.
Objective Spin refers to reporting strategies that highlight the benefits of an experimental treatment or divert attention from nonsignificant primary outcomes. To assess spin in randomized clinic trials (RCTs) on pharmaceutical efficacy in multiple sclerosis (MS) and explore associated factors.
Marta Mascareñas‐García   +10 more
wiley   +1 more source

Phase I pharmacokinetic study of etmaben, a malonic acid derivative

open access: yesРазработка и регистрация лекарственных средств
Introduction. Etmaben is a malonic acid derivative that has shown cardiotropic activity and is a promising candidate for treating ischemic heart disease and chronic heart failure.
P. K. Karnakova   +8 more
doaj   +1 more source

Approaches to conducting a physiologically relevant test (PRT) in the study of medicines containing substance IIc of the BCS subclass using sorafenib as an example

open access: yesРазработка и регистрация лекарственных средств
Introduction. Sorafenib is an antineoplastic drug belonging to class IIc according to the biopharmaceutical classification system (BCS) due to the presence of both acidic and basic properties.
A. V. Suvorova   +6 more
doaj   +1 more source

Limiting liability [PDF]

open access: yesJournal of Building Appraisal, 2006
openaire   +1 more source

Unlocking fruit dimensions: Quantification of functional traits driving plant–frugivore interactions

open access: yesApplications in Plant Sciences, EarlyView.
Abstract Fleshy fruits attract animals to ingest fruit, swallow the seeds, and release them in the landscape, thus facilitating seed dispersal and plant regeneration. Attraction of animal dispersers is achieved via attractants such as color or scent, and rewards like sugars, lipids, and micronutrients.
Linh M. N. Nguyen   +4 more
wiley   +1 more source

Comparative and functional anatomy of masticatory muscles and bite force in opossums (Didelphimorphia, Didelphidae)

open access: yesThe Anatomical Record, EarlyView.
We describe the functional anatomy of masticatory muscles in nine opossums, finding a generalized anatomical pattern with differences related to skull morphology. Variation in quantitative myological data and estimated bite force was mostly related to size, and the increase in bite force supports dietary diversification associated with size increase ...
Juann A. F. H. Abreu, Diego Astúa
wiley   +1 more source

Positioning control of reference units of automatic raising and leveling system of support platform

open access: yesInformatika, 2018
The questions of positioning control of reference units of automatic raising and leveling system of support platform were considered in the article. The list of functional elements which are needed for analyzing the hydraulic reference units behavior in ...
A. G. Strizhnev, A. A. Shykhau
doaj  

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