Results 21 to 30 of about 99,860 (313)

Application of the mathematical modeling of the processes of geofiltration and geomigration at the deposits of mineral waters of IV group of complexity (Kislovodsk deposits of mineral waters)

Известия высших учебных заведений: Геология и разведка, 2016
The important issue of constructing a mathematical model of the Kislovodsk mineral water deposit is considered. The hydrodynamic and hydrogeochemical regimes of the aquifers are characterized by highly dynamics, and depend both on the natural and ...
A. V. Malkov, I. S. Pomelyayko, V. F. Dubogrey, V. V. Khmel   +3 more
doaj   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The Results of International Educational Expeditions Aimed at the Russian Language, Literature, Culture and Russian Education Spread in the Near and Far-abroad Countries

Polylinguality and Transcultural Practices, 2020
The article considers the main approaches to expanding international cultural and humanitarian cooperation, ensuring educational, scientific and informational interaction between the Russian Federation and European countries through international ...
Natalya Yu. Mishina, Evgeniy A. Antonov
doaj   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Power quality disturbance detection method based on optimized kernel extreme learning machine [PDF]

MATEC Web of Conferences
In order to improve the accuracy of rapid detection of power quality, a power quality disturbance (PQD) classification method based on kernel-based extreme learning machine (KELM) is proposed, and chaos optimization is used to improve the global ...
Xu Lin, Zhao Chun, Guo Lisha, Xiong Jiayu, Liu Chang, Wang Zhuo, Wei Zhen, Liu Bo   +7 more
doaj   +1 more source

Unraveling the Difference in the Composition/Content of the Aroma Compounds in Different Tobacco Leaves: For Better Use

Journal of Chemistry, 2022
The composition/content of aroma compounds in tobacco leaves in the different producing areas varies too much, and it is very meaningful to develop advanced analysis techniques to investigate the composition/content-producing area correlation.
Tiejun Yan, Ping Zhou, Fei Long, Jing Liu, Fengguang Wu, Maolin Zhang, Jialei Liu   +6 more
doaj   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Client-centricity and clientocracy: evolution of approaches in public administration

Вестник университета
Transformation of approaches to public administration has an increasing tendency of using successful entrepreneurial experience proven by long-term practice in the market.
V. Yu. Razgulyaev, A. A. Golovin, E. F. Shamaeva   +2 more
doaj   +1 more source

Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt, Marius Ygonia, Ali Manouchehrinia, Philippe Lefrançois, Ingrid Kockum, Adil Harroud   +5 more
wiley   +1 more source

Grotius and Limited Liability

Grotiana, 2023
Abstract Grotius’s ideas on proportionate and limited liability, as mentioned in the Inleidinge and De iure belli ac pacis, were novel in comparison to the civilian doctrine of his time. Grotius drew from sources of local law and statutes regarding maritime law but was nonetheless original in his interpretations.
openaire   +3 more sources