Results 151 to 160 of about 195,901 (353)

Targeting GRP78 and the Proteostasis Network to Break the Therapeutic Ceiling in Neuroendocrine Prostate Cancer

iNew Medicine, EarlyView.
ABSTRACT HSPA5 (also known as GRP78/BiP) is a master regulator of the endoplasmic reticulum (ER) stress response and a key node in the proteostasis network. In neuroendocrine prostate cancer (NEPC), an aggressive, therapy‐refractory lineage that emerges under pressure from androgen receptor (AR) directed therapies, GRP78 is upregulated and co‐opted to ...
Amos Olalekan Akinyemi, Md Rakibul Alam, Mithu Howlader, Mohammad Esfini Farahani, Lixiang Gu, Chun Li, Chripus Ngule, Kevin Fulp, Bolaji Owoyemi, Xinyi Wang, Samuel Nwadialo, Fatemeh Selani, Makumba Esoe, Obaleye Oluwafunminiyi, Zhiguo Li   +14 more
wiley   +1 more source

Expanding Cystic Fibrosis Registries to the Rest of the World. [PDF]

Pediatr Pulmonol
Naehrlich L.
europepmc   +1 more source

Individual Auditor Legal Liability and Collaborative Networks: Evidence from Mandatory Changes to Limited Liability Partnerships in China

Daniel Aobdia, Zihui Li, Keyuan Zhang, Min Zhang   +3 more
openalex   +1 more source

Navigating the Uncertainty: Unveiling the Impact of Trade Policy Uncertainty on GVC Ascent in Chinese Listed Companies

International Studies of Economics, EarlyView.
ABSTRACT This study is based on real options theory and uses a sample of Chinese listed companies from 2000 to 2016 to investigate the dynamic process and mechanisms by which trade policy uncertainty affects the upgrading of enterprises within the global value chain (GVC). The article finds that trade policy uncertainty has a positive forcing effect on
Shiyi Wu, Rui Niu
wiley   +1 more source

Hype vs Reality in the Integration of Artificial Intelligence in Clinical Workflows. [PDF]

JMIR Form Res
Abd-Alrazaq A, Solaiman B, Mekki YM, Al-Thani D, Farooq F, Alkubeyyer M, Abubacker MZ, AlSaad R, Aziz S, Serag A, Thomas R, Sheikh J, Ahmed A.   +12 more
europepmc   +1 more source

Narrow Framing in Risk Aversion Experiments: Further Evidence From a Wide Replication

Journal of Applied Econometrics, EarlyView.
ABSTRACT When evaluating risky options in experimental settings, do individuals integrate background finances with experimental earnings? An existing study, which combines experimental data on lottery choices and administrative data on personal wealth in Denmark, shows that individuals evaluate experimental payoffs in isolation.
Ariel Gu, Matthew J. Walker, Hong Il Yoo
wiley   +1 more source

Embrace the tension: a decolonial reframing of Implementation Science. [PDF]

BMJ Glob Health
Mascayano F, Rivera E, Montenegro C, Bass JK.   +3 more
europepmc   +1 more source

Understanding Substance Use and Suicide Risk Among LGBTQ+ College Students Post‐COVID‐19

Journal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This study examines the reported frequency of substance use, levels of suicide risk, and their relationships among LGBTQ+ college students (N = 192) following the COVID‐19 pandemic. Participants most commonly reported alcohol and marijuana use, and least commonly reported unprescribed prescription opioid or heroin use.
Afroze N. Shaikh, Jordan B. Westcott, Brittney N. R. Irion, Jackie Yang, Illiana R. Navarra‐Bueno, Hannah Martinson, Noah Diaz   +6 more
wiley   +1 more source

The role of social and genetic factors in partnership trajectories and later life health. [PDF]

Sci Rep
Lin MJ.
europepmc   +1 more source

The Effect of Limited Liability Partnership on Audit Fee and Audit Hour

, 2019
Sohee Woo, 김범수
openalex   +1 more source