Results 181 to 190 of about 4,089,631 (323)

Les limites aux faits justificatifs [PDF]

, 2008
C. Duparc
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

[Planetary health: The inescapable role of family medicine]. [PDF]

Aten Primaria
Galindo Ortega G, Del Campo Giménez M, Gutiérrez Muñoz B, Navarro Beltrá M, Almécija Pérez MC.   +4 more
europepmc   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Beyond Limits: What 366 Consecutive Marathons Reveal about the Human Heart. [PDF]

Arq Bras Cardiol
Braga F, Stein R.
europepmc   +1 more source

Tangent unit-vector fields: nonabelian\ud homotopy invariants and the Dirichlet energy [PDF]

, 2009
Majumdar, A., Robbins, J M, Zyskin, M
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

[Results and limitations in surgery for Lipedema, Lymphedema and Elephantiasis of the lower limbs in a resource-limited country: Democratic Republic of Congo, 2010 to 2025]. [PDF]

Pan Afr Med J
Kibadi-Kapay A.
europepmc   +1 more source

Les limites de la croissance [PDF]

, 1991
Albaigés, J. (Joan)
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source