Results 231 to 240 of about 3,333,618 (304)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

[Infectious tenosynovitis as an unusual focus of septic shock: A case report]. [PDF]

open access: yesAten Primaria
Mora-Aznar M   +2 more
europepmc   +1 more source

The social imaginary in the daily lives of family caregivers during the prevention of childhood tuberculosis in southern Lima, Peru. [PDF]

open access: yesRev Peru Med Exp Salud Publica
Zeladita-Huaman JA   +5 more
europepmc   +1 more source

Experiences of older people in Long-Term Care Institutions in light of the theory of Liquid Modernity. [PDF]

open access: yesRev Esc Enferm USP
Oliveira MA   +5 more
europepmc   +1 more source

Parenting and stimulation for child development at home: perspectives from Nurturing Care. [PDF]

open access: yesRev Lat Am Enfermagem
Hilário JSM   +4 more
europepmc   +1 more source

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