Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Protégeons les jeunes du Canada contre les risques associés à l’exposition à la publicité sur le jeu. [PDF]
Charlebois S, Kelly S.
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Serum Levels of sCD40L, CCL3, and NT-proBNP in Elderly Patients Admitted to the Hospital with HF. [PDF]
Horta MDGC, Borin MC.
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
[Infectious tenosynovitis as an unusual focus of septic shock: A case report]. [PDF]
Mora-Aznar M +2 more
europepmc +1 more source
The social imaginary in the daily lives of family caregivers during the prevention of childhood tuberculosis in southern Lima, Peru. [PDF]
Zeladita-Huaman JA +5 more
europepmc +1 more source
Experiences of older people in Long-Term Care Institutions in light of the theory of Liquid Modernity. [PDF]
Oliveira MA +5 more
europepmc +1 more source
Embolie pulmonaire à risque intermédiaire–élevé chez une femme de 53 ans présentant un cancer colorectal et une contre-indication à la thrombolyse. [PDF]
Hanson NL, Utgikar R, Bokhari M, Tan KT.
europepmc +1 more source
Parenting and stimulation for child development at home: perspectives from Nurturing Care. [PDF]
Hilário JSM +4 more
europepmc +1 more source

