Results 91 to 100 of about 4,401,793 (267)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Limiting Network Size within Finite Bounds for Optimization
, 2019 Largest theoretical contribution to Neural Networks comes from VC Dimension which characterizes the sample complexity of classification model in a probabilistic view and are widely used to study the generalization error.
Gopalan, Dr. Sasi, Pinto, Linu
core
Nature Reviews Cancer, 2008 The use of agents that modulate tumour angiogenesis has led to improvements in patient care, and tumour angiogenesis remains an important area for cancer research. As more anti-angiogenic agents proceed through clinical development, it is important to consider what we now know about the effects these agents have on the tumour vasculature and what ...
openaire +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
International Journal of Electrical Power & Energy SystemsThe DC circuit breaker (DCCB) is a critical device that ensures the safe and reliable operation of the DC transmission system. As the level of DC voltage and transmission power increases, the flexible DC grid will need more and more opening capacity of ...
Hongchun Shu, Zongxue Shao, Yue Dai
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Exact limiting solutions for certain deterministic traffic rules
, 2001 We analyze the steady-state flow as a function of the initial density for a class of deterministic cellular automata rules (``traffic rules'') with periodic boundary conditions [H. Fuks and N. Boccara, Int. J. Mod. Phys. C 9, 1 (1998)].
Kujala, Janne V., Lukka, Tuomas J.
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Corrigendum: Seed Composition and Amino Acid Profiles for Quinoa Grown in Washington State
Frontiers in Nutrition, 2020 Evan B. Craine, Kevin M. Murphy
doaj +1 more source
Performance limiting effects in X-band accelerators
Physical Review Special Topics. Accelerators and Beams, 2011 Acceleration gradient is a critical parameter for the design of future TeV-scale linear colliders. The major obstacle to higher gradient in room-temperature accelerators is rf breakdown, which is still a very mysterious phenomenon that depends on the ...
Faya Wang +2 more
doaj +1 more source