Results 211 to 220 of about 5,095,179 (363)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Targeted dual selection to optimize transposon stable pool generation of multispecifics. [PDF]

MAbs
Johnston J, Tierson S, Xu Y, Mix K, Guo YJ, Zenger S, Reczek D, Hoffmann D, Hall B, Brophy V.   +9 more
europepmc   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Perfluorocarbon liquid-assisted inverted multilayer internal limiting membrane flaps covering for macular hole retinal detachment in high myopia with axial length ≥30 mm. [PDF]

Int J Ophthalmol
Wang LP, Dang WJ, Yan H, Gong K, Deng J, Sun WT.   +5 more
europepmc   +1 more source

Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light

Cell, 2016
Ullas V. Pedmale, S. Huang, Mark Zander, Benjamin J. Cole, Jonathan Hetzel, K. Ljung, P. A. Reis, P. Sridevi, K. Nito, Joseph R. Nery, J. Ecker, J. Chory   +11 more
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Limiting Auditors’ Liability [PDF]

Bond Law Review
Clinton Free
doaj  

Analysis of qPCR Data: From PCR Efficiency to Absolute Target Quantity. [PDF]

Int J Mol Sci
Ruijter JM, van den Hoff MJB.
europepmc   +1 more source

Modulation of the bacterial response to spectral solar radiation by algae and limiting nutrients [PDF]

, 2002
Juan Manuel Medina‐Sánchez, Manuel Villar‐Argáiz, Presentación Carrillo   +2 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source