Results 221 to 230 of about 5,095,179 (363)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Malfunction of adjustable pressure limiting valve

Journal of Anaesthesiology Clinical Pharmacology, 2017
Apoorv Upendra Chaturvedi, Meenoti Pramod Potdar   +1 more
doaj   +1 more source

The Role of Beef for the Lowest Cost and Adequate Provision of Bioavailable Nutrients in Modeled Diets at a Population Level in the United States. [PDF]

Curr Dev Nutr
Chungchunlam SM, Moughan PJ.
europepmc   +1 more source

Involvement of WalK (VicK) phosphatase activity in setting WalR (VicR) response regulator phosphorylation level and limiting cross‐talk in Streptococcus pneumoniaeD39 cells

, 2012
Kyle J. Wayne, Shuo Li, Krystyna M. Kazmierczak, Ho‐Ching Tiffany Tsui, Malcolm E. Winkler   +4 more
openalex   +2 more sources

Preventative releases of self-limiting Ceratitis capitata provide pest suppression and protect fruit quality in outdoor netted cages [PDF]

, 2019
Romisa Asadi, Rachid Elaini, Renaud Lacroix, Thomas H. Ant, Amandine Collado, Lucy Finnegan, Paolo Siciliano, Ahmed Mazih, Martha Koukidou   +8 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Consistency and limiting distribution of the least squares estimator of a threshold autoregressive model

, 1993
K. Chan
semanticscholar   +1 more source

Fishy limits [PDF]

Nature, 2015
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

NLRP6 Protects Il10-/- Mice from Colitis by Limiting Colonization of Akkermansia muciniphila.

Cell Reports, 2017
S. Seregin, Natasha B Golovchenko, Bryan Schaf, Jiachen Chen, Nicholas A. Pudlo, Jonathan S. Mitchell, Nielson T. Baxter, Lili Zhao, P. Schloss, E. Martens, K. Eaton, Grace Y. Chen   +11 more
semanticscholar   +1 more source