Results 91 to 100 of about 1,651,766 (269)
Topology and its Applications, 2010 Soient \(X\) un espace métrique compact et \(f\) une fonction multivoque semi-continue supérieurement (s.c.s.) de \(X\) dans lui-même. Soit \(\varprojlim \{X,f\}\) la limite de la suite projective \((X_i,f_i)\) où, pour tout \(i\), \(X_i=X\) et \(f_i:X_{i+1}\to X_i\) est une copie de \(f\). Cette limite projective est regardée comme un sous-ensemble du
Banič, Iztok +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Limits of Autonomy Principle in Documentary Letters of Credit; Perspective of English Law
Journal of Legal Studies, 2017 In this article, the author reviews the approach of English courts to limits of autonomy principle and tries to answer the following research questions: What obligations should the applicant fulfil while opening a credit in accordance with the underlying
Alavi Hamed
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The European Journal of Humour Research, 2015 In the vernacular ideology of humour there are definite ideas about where the limits of joke acceptability lie. In practice, many joke performances seem to go beyond those limits and yet arouse little if any opposition. This paper considers the role that
Moira Marsh
doaj
Ribogospodarsʹka Nauka UkraïniPurpose. To analyze and summarize the biological parameters of the main commercial species of aquatic bioresources using the example of bream, common carp, roach, Prussian carp and pikeperch of the Zaporizhzhia (Dnipro) Reservoir under conditions of ...
O. Marenkov +4 more
doaj +1 more source