Results 251 to 260 of about 2,942,734 (312)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Semantically Constrained Detection of Systemic Archetype-Inspired Patterns in Idiographic Case Formulations: A Rule-Based Framework Using FCM-FRHP Functional Semantics. [PDF]

Eur J Investig Health Psychol Educ
Hurtado-Martínez C, Botella L, Sanfeliciano A, Aranda-Escolástico E, Saúl LA.   +4 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Analytical Agreement Between the Vision C Automated ESR Analyzer and the Manual Westergren Reference Method: A Prospective Method Comparison Study. [PDF]

Diagnostics (Basel)
Tuzcu A, Yörük K, Kurtulmuş Y, Yılmaz M.   +3 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Evaluation of a Wearable Device for Cardiorespiratory Monitoring in Healthy Anaesthetised Cats. [PDF]

Vet Med Sci
Melek Ş, Orhun ÖT, Şenocak MG, Arslan T.   +3 more
europepmc   +1 more source

Automated measurement of Little's Irregularity Index on intraoral photographs using a convolutional neural network. [PDF]

BMC Oral Health
Kanemeier M, Ergün T, Stamm T, Middelberg C, Schmid JQ.   +4 more
europepmc   +1 more source