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9th International Conference on Biosystems Engineering 2018 : Book of Abstracts : 9-11 May 2018 [PDF]

open access: yes, 2018
Full textBook of Abstracts. 9th International Conference on Biosystems Engineering 2018, May 9–11, 2018 Tartu, Estonia.
Estonian University of Life Sciences
core   +1 more source

Post-licensure biological product specification adjustment & alignment: demonstration of statistical methodologies through case studies

open access: yesAAPS Open
The post-licensure re-evaluation of specifications for critical quality attributes (CQAs) is a vital component of the biologics lifecycle. This process is driven by evolving manufacturing practices, regulatory requirements, and an enhanced understanding ...
Shyam Panjwani, Konstantinos Spetsieris
doaj   +1 more source

RIBOS TARP PRAMANO IR TIKROVĖS: FENOMENOLOGINĖ PERSPEKTYVA

open access: yesProblemos, 2006
Straipsnyje nagrinėjama riba tarp tikrovės ir meninės išmonės, siekiama nustatyti pastarosios vietą mūsų gyvenamojoje visumoje. Vadovaujamasi fenomenologine perspektyva, kuri papildoma Aristotelio judrios realybės samprata ir Bachtino estetine žiūra. Tai
Tomas Kačerauskas
doaj   +1 more source

Hypotheses, Limits, Models and Life [PDF]

open access: yesLife, 2014
Life is launching a new section, called Hypotheses in the Life Sciences. The new Section will complement the other sections of Life, providing a feedstock of ideas whose tests can be published in the wider Life family, and elsewhere. We will consider hypotheses that are supported by real world, rigorous evidence, by clear arguments, and which provide a
openaire   +3 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Information-theoretic limits of health indicator construction for remaining useful life prediction

open access: yesEngineering Science and Technology, an International Journal
In data-driven remaining useful life (RUL) prediction, practitioners face a recurring design choice: should engineering effort focus on health indicator (HI) construction or on model architecture?
Huy Hoang Le, Kim-Anh Nguyen
doaj   +1 more source

THE LIMITS OF PRAGMATISM IN EDUCATION AND TRAINING AS A FACTOR INFLUENCING THE QUALITY OF LIFE

open access: yesActa Metallurgica Slovaca, 2017
Characteristics of the development of education system of the Slovak Republic ,, The Enlightenment demands nothing but freedom-freedom that lies in the public use of reason and, that is, under any circumstances.
Vladimír Vodzinský
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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