Results 101 to 110 of about 390 (142)

DIFFERENTIAL PHOSPHORYLATIONS OF NFKB AND CELL GROWTH OF MDA-MB 231 HUMAN BREAST CANCER CELL LINE BY LIMONINS

core   +1 more source

Unusual Vilasinin-Class Limonoids from Trichilia rubescens. [PDF]

Molecules
Amuti S, Saito Y, Fukuyoshi S, Miyake K, Newman DJ, O'Keefe BR, Lee KH, Nakagawa-Goto K.   +7 more
europepmc   +1 more source

The integration of multidisciplinary approaches revealed PTGES3 as a novel drug target for breast cancer treatment. [PDF]

J Transl Med
Yin Q, Ma H, Dong Y, Zhang S, Wang J, Liang J, Mao L, Zeng L, Xiong X, Chen X, Wang J, Zheng X.   +11 more
europepmc   +1 more source

Assessment of the in vitro anti-diabetic activity with molecular dynamic simulations of limonoids isolated from Adalia lemon peels. [PDF]

Sci Rep
El-Feky AM, Aboulthana WM, El-Rashedy AA.   +2 more
europepmc   +1 more source

Lefamulin Overcomes Acquired Drug Resistance via Regulating Mitochondrial Homeostasis by Targeting ILF3 in Hepatocellular Carcinoma. [PDF]

Adv Sci (Weinh)
Zheng Y, Ye S, Huang S, Cheng Y, Zhang Y, Leng Y, He M, Wu E, Chen J, Kong L, Zhang H.   +10 more
europepmc   +1 more source

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Total Synthesis of Limonin

Angewandte Chemie International Edition, 2015
AbstractLimonoids are highly oxygenated C13α‐triterpenes and common secondary metabolites. Several hundred congeners have been isolated to date. The first total synthesis of (±)‐limonin, the flagship congener of the limonoids, is now reported and features 1) a tandem radical cyclization generating the BCD ring system with the C13α configuration that is
Shuji, Yamashita, Akito, Naruko, Yuki, Nakazawa, Le, Zhao, Yujiro, Hayashi, Masahiro, Hirama   +5 more
openaire   +2 more sources

Evaluation of the Antioxidant Capacity of Limonin, Nomilin, and Limonin Glucoside

Journal of Agricultural and Food Chemistry, 2006
The antioxidant capacity (AOC) of three representative citrus limonoids, limonin, nomilin, and limonin glucoside, was examined by the oxygen radical absorbance capacity (ORAC), Trolox equivalent antioxidant capacity (TEAC), beta-carotene-linoleic acid bleaching, and 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging assays.
Andrew P, Breksa, Gary D, Manners
openaire   +2 more sources

The structure of limonin

Experientia, 1960
Die Struktur desepi-Limonol-jodoacetates (C26H31O8) COCH2I, wurde durch dreidimensionale Rontgenanalyse bestimmt. Es gelang, die Lage samtlicher Atome in zwei kristallographisch unabhangigen, jedoch chemisch identischen Molekeln zu ermitteln. Dieses Resultat stellt eine vollstandige Bestimmung der Konstitution und der Stereochemie des Limonins dar.
S. Arnott, A. W. Davie, J. M. Robertson, G. A. Sim, D. G. Watson   +4 more
openaire   +1 more source

Gender differences in limonin pharmacokinetics in rats

European Journal of Drug Metabolism and Pharmacokinetics, 2005
In the present study, the pharmacokinetics of limonin (LM) were investigated in male and female rats. LM concentrations in the plasma were determined after the oral administration of 36 mg/kg LM or after intravenous (i.v.) injection of LM 3.6 mg/kg respectively.
Y, Liang, L, Xie, X D, Liu, Y Z, Hu, T, Lu, G J, Wang   +5 more
openaire   +2 more sources

Limonin ameliorates cardiovascular dysfunction and remodeling in hypertensive rats

Life Sciences, 2023
Limonin is a tetracyclic triterpenoid isolated from citrus fruits. Here, the effects of limonin on cardiovascular abnormalities in nitric oxide-deficient rats induced by Nω-Nitrol-arginine methyl ester (L-NAME) were explored.Male Sprague Dawley rats were given L-NAME (40 mg/kg, drinking water) for 3 weeks and then treated daily with polyethylene glycol
Metee, Iampanichakul, Prapassorn, Potue, Siwayu, Rattanakanokchai, Putcharawipa, Maneesai, Juthamas, Khamseekaew, Wannapa, Settheetham-Ishida, Poungrat, Pakdeechote   +6 more
openaire   +2 more sources