Results 101 to 110 of about 1,925,354 (247)
On the synergy between myelin proteins P0, MBP, and P2 in peripheral nerve major dense line formation. [PDF]
Krokengen OC +9 more
europepmc +1 more source
Hanle‐Zeeman Redistribution Matrix. III. Solution of the Polarized Line Formation Problem [PDF]
M. Sampoorna +2 more
openalex +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Doubly uniparental inheritance of mitochondria as a model system for studying germ line formation. [PDF]
Milani L +3 more
europepmc +1 more source
The Formation of Absorption Lines [PDF]
openaire +1 more source
Toward a Deterministic Model of Planetary Formation. V. Accumulation Near the Ice Line and Super‐Earths [PDF]
Shigeru Ida, D. N. C. Lin
openalex +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source

