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LINE-1: A mammalian transposable element

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1987
T G, Fanning, M F, Singer
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LINE-1

2010
V. Stribinskis, K.S. Ramos
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LINE-1 retrotransposons in cancer

A LINE-1 retrotranszpozonok az egyetlen ma is aktív transzpozábilis elemek az emberi genomban. Az ORF1 és ORF2 fehérjéket kódolják, melyek elengedhetetlenek a „másolás és beillesztés” típusú replikációs mechanizmusukhoz. A LINE-1 szekvenciák az emberi genom 17%-át alkotják, körülbelül 500 000 kópiával, amelyek közül 100-150 retrotranszpozícióra képes ...
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LINE-1 Elements

2008
Suzanne M. Benjes, Christine M. Morris
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LINE-1 in cervical cancers

Global hypomethylation may potentially promote carcinogenesis via at least three possible mechanisms: activation of oncogenes, reactivation of transposable elements and genomic instability. The thesis aims to study the mechanism of global hypomethylation induces genomic instability.
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Naples Underground Line 1

V. Manassero, F. Giannelli, S. Spada
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