Results 121 to 130 of about 10,781,633 (341)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Wetting of doubly periodic rough surfaces in Wenzel’s regime

open access: yesMATEC Web of Conferences, 2018
In this work we present preliminary results from our numerical study of the shapes of a liquid meniscus in contact with doubly sinusoidal rough surfaces in Wenzel’s wetting regime.
Iliev Stanimir   +2 more
doaj   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Freezing receding contact lines

open access: yes
We investigate experimentally the receding of a contact line when a Peltier module is pulled out of a water bath at constant speed, while a ice layer is also growing at constant speed on the Peltier module. A steady regime is therefore reached for all the parameters used in this studied, corresponding to a dynamical stationnary meniscus.
Grivet, Rodolphe   +4 more
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Analysis of Dynamic Wetting and Dewetting on a Hydrophobic Surface Using Molecular Kinetic Theory

open access: yesTribology Online
The dynamic wetting and dewetting of a water droplet on a hydrophobic solid surface with an equilibrium contact angle of approximately 100° was investigated using molecular kinetic (MK) theory to model the extension–contraction experiment and numerically
Chinatsu Saito   +3 more
doaj   +1 more source

Study of instantaneous starvation at a finite-length line contact [PDF]

open access: yesJurnal Tribologi, 2019
Starvation phenomenon widely exists in the non-conforming contacts when high-viscosity lubricating oil or greases are used. However, most of the work focuses on the steady state starvation, and the phenomenon of instantaneous starvation is not well ...
Xuejin Shen   +3 more
doaj  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

THE EXCESS-VOLTAGE PROTECTION OF ELECTRIC TRACTION NETWORKS OF DIRECT CURRENT. THE METHODOLOGY OF CHOOSING SURGE PROTECTION DEVICE

open access: yesNauka ta progres transportu, 2010
The article is dealt with the selecting methodology of overvoltage arresters for DC traction line.
Ye. D. Kim, V. H. Sychenko
doaj  

Home - About - Disclaimer - Privacy