Results 81 to 90 of about 1,940,264 (298)
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Eos, Transactions American Geophysical Union, 2001 In the United States, along with the decennial census comes the once‐per‐decade task of redistricting. Redistricting is the drawing of legislative district boundaries in response to changes in state population totals, with the goal of assuring as near‐equal representation of each person as is practicable.
openaire +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Do You Like Sclera? Sclera-region Detection and Colorization for Anime Character Line Drawings
International Journal of Networked and Distributed Computing (IJNDC)Colorizing line drawings requires special skill, experience, and knowledge. Artists also spend a great deal of time and effort creating art. Given this background, research on automated line drawing colorization was recently conducted.
Masashi Aizawa +4 more
doaj +1 more source
A Center Transversal Theorem for Hyperplanes and Applications to Graph Drawing
, 2011 Motivated by an open problem from graph drawing, we study several partitioning problems for line and hyperplane arrangements. We prove a ham-sandwich cut theorem: given two sets of n lines in R^2, there is a line l such that in both line sets, for both ...
Dujmovic, Vida, Langerman, Stefan
core +3 more sources
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Drawing the line: balancing the spatial requirements of customer and contractor in occupied refurbishment [PDF]
, 2003 In planning the refurbishment of railway stations the spatial needs of the contractor and ofthe ongoing business stakeholders have to be balanced.
Kelsey, JM
core
On the Maximum Crossing Number
, 2017 Research about crossings is typically about minimization. In this paper, we consider \emph{maximizing} the number of crossings over all possible ways to draw a given graph in the plane. Alpert et al. [Electron. J.
E Steinitz +18 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source