Results 91 to 100 of about 143,470 (303)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

基于接触强度的直动滚子凸轮基本尺寸设计

open access: yesJixie chuandong, 2008
The contact stress calculation of the plate cam mechanism with translating roller-moving follower based of the Hertz contact theory is studied.The methods what are used to calculate the synthesis curvature radius of cam,contact line length of follower ...
廖海平, 刘启跃, 陈兴, 杨军
doaj  

Simulation Of A Trash Can Using Line Follower Based On Arduino

open access: yesJournal of Technology Informatics and Engineering
There is a lot of dirt scattered around the State Elementary School (SDN) 03 Purwoyoso, Semarang. The habit of elementary school children and their parents is that they often throw rubbish everywhere and are lazy about throwing away the rubbish.
Iqbal Hakim, Andik Prakasa Hadi
doaj   +1 more source

ALGORITMA FLOODFILL UNTUK MENENTUKAN TITIK KOORDINAT MAZE MAPPING PADA ROBOT LINEFOLLOWER

open access: yesSimetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2016
Robot line follower (RLF) adalah robot yang dapat berjalan mengikuti suatu maze yang berupa garis secara otomatis. RLF dapat digunakan untuk aplikasi pengiriman barang dari suatu tempat awal ke tempat tujuan dengan cepat, tepat dan akurat.
Ary Sulistyo Utomo
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Low-frequency noise impact on CMOS image sensors [PDF]

open access: yes, 2009
CMOS image sensors are nowadays extensively used in imaging applications even for high-end applications. This is really possible thanks to a reduction of noise obtained, among others, by Correlated Double Sampling (CDS) readout.
Magnan, Pierre   +1 more
core  

Mobile Formation Coordination and Tracking Control for Multiple Non-holonomic Vehicles

open access: yes, 2019
This paper addresses forward motion control for trajectory tracking and mobile formation coordination for a group of non-holonomic vehicles on SE(2). Firstly, by constructing an intermediate attitude variable which involves vehicles' position information
Geng, Zhiyong,   +4 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

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