Results 71 to 80 of about 1,577,958 (284)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Atmosphere, 2021 The reparameterization of the geometry-free and geometry-based approaches to derive single-site ionospheric delays using Global Navigation Satellite System (GNSS) measurements is described.
Sijing Liu +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Nonintrusive overhead‐line current detection using a vertical magnetic‐field sensor array
IET Generation, Transmission & Distribution, 2023 With the growing infrastructure for overhead lines, the demand for overhead‐line condition‐monitoring technologies has become increasingly urgent. Traditional current transformers used to measure three‐phase currents are bulky and difficult to install ...
Kun‐Long Chen +2 more
doaj +1 more source
New topological recursion relations
, 2010 Simple boundary expressions for the k-th power of the cotangent line class on the moduli space of stable 1-pointed genus g curves are found for k >= 2g. The method is by virtual localization on the moduli space of maps to the projective line.
Liu, Xiaobo, Pandharipande, Rahul
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
Probabilistic Geometry Based on the Fuzzy Playfair Axiom
FoundationsA probabilistic version of geometry is introduced. The fifth postulate of Euclid (Playfair’s axiom) is adopted in the following probabilistic form: consider a line and a point not on the line—there is exactly one line through the point with probability P,
Edward Bormashenko
doaj +1 more source
An Epipolar Line from a Single Pixel
, 2018 Computing the epipolar geometry from feature points between cameras with very different viewpoints is often error prone, as an object's appearance can vary greatly between images.
Halperin, Tavi, Werman, Michael
core +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Line-closed combinatorial geometries
Discrete Mathematics, 1987 We present some results on combinatorial geometries (geometric lattices) in which closure is line-closure. We prove that every interval of a line- closed geometry is line-closed. Furthermore, if every rank 3 interval of a geometry is line-closed, then the geometry is line-closed. This implies that every supersolvable geometry is line-closed. Though not
openaire +2 more sources