Results 251 to 260 of about 10,265,072 (333)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

open access: yesAdvanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj   +21 more
wiley   +1 more source

Compaction of chromatin domains regulates target search times of proteins. [PDF]

open access: yesPLoS Comput Biol
Dutta S   +3 more
europepmc   +1 more source

Tailoring On-line Search Retrieval.

open access: yesBulletin of the Medical Library Association, 2010
openaire   +1 more source

A simple uniformly optimal method without line search for convex optimization

Mathematical programming, 2023
Line search (or backtracking) procedures have been widely employed into first-order methods for solving convex optimization problems, especially those with unknown problem parameters (e.g., Lipschitz constant).
Tianjiao Li, Guanghui Lan
semanticscholar   +1 more source

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