Results 141 to 150 of about 19,833 (300)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 2015 Estimating of combining ability is useful to assess genotypes and elucidate the nature and magnitude of gene actions involved. Aim of this study was to determine the combining abilities of some wheat genotypes for yield and some yield related traits by ...
Tosun, Muzaffer +4 more
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Line x Tester Analysis in Sesame (Sesamum indicum L.)
International Journal of Current Microbiology and Applied Sciences, 2017 Kanak Saxena, Rajani Bisen
openaire +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
, 2019 MAYDICAThis study evaluated seven inbred lines of maize (Zea mays L.), three testers and 21 hybrids produced by line x tester mating design. Stomatal conductance, chlorophyll content, photosynthetic efficiency, and transpiration rate traits of parents ...
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GENE ACTION AND HETEROSIS THROUGH LINE x TESTER ANALYSIS IN Brassica napus L. [PDF]
, 2012 A Thesis Sufimited to the Faculty of Agricufture, Sher-e-Bangla Agricultura University, Dhaka, in partial filfillment of the requirements for the Degree of MASTER OF SCIENCE IN GENETICS AND PLANT BREEDING SEMESTER: JULY-DECEMBER, 2012The study ...
AFROSE, RASHMA
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
COMBINING ABILITY AND HETEROSIS IN Brassica napus L. USING LINE-TESTER METHOD [PDF]
, 2014 A Thesis Submitted to the Faculty of Agriculture Sher-e-Bangla Agricultural University, Dhaka, in partial fulfillment of the requirements for the degree of MASTER OF SCIENCE IN GENETICS AND PLANT BREEDING SEMESTER: JANUARY-JUNE, 2014An experiment
ISMAIL, SABRINA
core
Study of Combining Ability in Maize Line x Tester Hybridization
Pakistan Journal of Biological Sciences, 1998 M. R. Hussain, K. Aziz
openaire +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source