Systems genetic analysis of osteoblast-lineage cells. [PDF]
PLoS Genetics, 2012 The osteoblast-lineage consists of cells at various stages of maturation that are essential for skeletal development, growth, and maintenance. Over the past decade, many of the signaling cascades that regulate this lineage have been elucidated; however ...
Gina Calabrese +8 more
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Inter- and intra-lineage genetic diversity of wild-type Zika viruses reveals both common and distinctive nucleotide variants and clusters of genomic diversity [PDF]
Emerging Microbes and Infections, 2019 Zika virus (ZIKV) strains belong to the East African, West African, and Asian/American phylogenetic lineages. RNA viruses, like ZIKV, exist as populations of genetically-related sequences whose heterogeneity may impact viral fitness, evolution, and ...
Natalie D. Collins +6 more
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Genetic flux over time in the Salmonella lineage [PDF]
Genome Biology, 2007 Abstract Background DNA sequences that are shared between closely related organisms while being absent from their common ancestor and from sister lineages of that ancestor are likely to have been acquired by horizontal gene transfer.
Georgios S Vernikos +2 more
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Genetic and epigenetic variation in the lineage specification of regulatory T cells
eLife, 2015 Regulatory T (Treg) cells, which suppress autoimmunity and other inflammatory states, are characterized by a distinct set of genetic elements controlling their gene expression.
Aaron Arvey +5 more
doaj +4 more sources
A library of lineage-specific driver lines connects developing neuronal circuits to behavior in the Drosophila ventral nerve cord [PDF]
eLifeUnderstanding developmental changes in neuronal lineages is crucial to elucidate how they assemble into functional neural networks. Studies investigating nervous system development in model systems have only focused on select regions of the CNS due to ...
Jelly HM Soffers +11 more
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Generation of virus genetic lineages during an outbreak of poliomyelitis
Journal of General Virology, 1991 Wild poliovirus type 3 isolates collected during the Finnish outbreak (1984 to 1985) in different geographical locations were compared by partial RNA sequencing. The entire 5' non-coding end and a discontinuous part of the capsid coding region were sequenced from 15 isolates.
Leena Kinnunen, Tuija Pöyry, T Hovi
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Genetic structure and geographical distribution of Bithynia siamensis sensu lato from Khong and Mounlapamok districts, Champasak Province, Laos [PDF]
Tropical Medicine and HealthBackground Bithynia spp., a key intermediate host of Opisthorchis viverrini, is widely distributed in the lower Mekong sub-region, where opisthorchiasis remains a major public health concern.
Naruemon Bunchom +10 more
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Molecular epidemiology of Crimean-Congo hemorrhagic fever virus in Russia.
PLoS ONE, 2022 In this report, we present new data on the diversity and geographical distribution of genetic variants in Crimean-Congo hemorrhagic fever virus (CCHFV) in Russia.
Anna Volynkina +8 more
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Cre-loxP-mediated genetic lineage tracing: Unraveling cell fate and origin in the developing heart
Frontiers in Cardiovascular Medicine, 2023 The Cre-loxP-mediated genetic lineage tracing system is essential for constructing the fate mapping of single-cell progeny or cell populations. Understanding the structural hierarchy of cardiac progenitor cells facilitates unraveling cell fate and origin
Tao Wang +7 more
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Genetic Mosaics and the Germ Line Lineage [PDF]
Genes, 2015 Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the new mutation arises.
Samuels, Mark E., Friedman, Jan M.
openaire +4 more sources