Inter- and intra-lineage genetic diversity of wild-type Zika viruses reveals both common and distinctive nucleotide variants and clusters of genomic diversity [PDF]
Emerging Microbes and Infections, 2019 Zika virus (ZIKV) strains belong to the East African, West African, and Asian/American phylogenetic lineages. RNA viruses, like ZIKV, exist as populations of genetically-related sequences whose heterogeneity may impact viral fitness, evolution, and ...
Natalie D. Collins +6 more
doaj +3 more sources
Building a lineage from single cells: genetic techniques for cell lineage tracking [PDF]
Nature Reviews Genetics, 2017 Resolving lineage relationships between cells in an organism is a fundamental interest of developmental biology. Furthermore, investigating lineage can drive understanding of pathological states, including cancer, as well as understanding of developmental pathways that are amenable to manipulation by directed differentiation.
Mollie B. Woodworth +2 more
semanticscholar +3 more sources
Genetic Mosaics and the Germ Line Lineage [PDF]
Genes, 2015 Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the
M. Samuels, J. Friedman
semanticscholar +5 more sources
Systems genetic analysis of osteoblast-lineage cells. [PDF]
PLoS Genetics, 2012 The osteoblast-lineage consists of cells at various stages of maturation that are essential for skeletal development, growth, and maintenance. Over the past decade, many of the signaling cascades that regulate this lineage have been elucidated; however ...
Gina Calabrese +8 more
doaj +5 more sources
Three distinct genetic lineages of Trichonephila clavata based on mitochondrial COI and genome-wide SNPs on the Korean Peninsula [PDF]
Scientific ReportsTrichonephila clavata L. Koch, 1878, an East Asian species renowned for its long-distance ballooning dispersal, has recently drawn attention as an invasive species following its introduction into the southeastern United States.
Gyeongmin Kim +2 more
doaj +2 more sources
Whole‐Genome Resequencing Reveals the Demographic History and Adaptive Evolution of Tamarix austromongolica in the Yellow River Basin [PDF]
Ecology and EvolutionTamarix austromongolica is a native species widely used for ecological restoration in the Yellow River basin. Its natural distribution aligns with the river's strong environmental gradients.
Shuai Gong +5 more
doaj +2 more sources
Genetic and epigenetic variation in the lineage specification of regulatory T cells
eLife, 2015 Regulatory T (Treg) cells, which suppress autoimmunity and other inflammatory states, are characterized by a distinct set of genetic elements controlling their gene expression.
Aaron Arvey +5 more
doaj +2 more sources
Molecular phylogeny and species delimitation unravel climate-driven diversification and cryptic radiation in Iranian steppe Vipers (Vipera ursinii-renardi complex) [PDF]
Scientific ReportsAccurate delineation of biodiversity units is essential for effective conservation, particularly in species complexes with cryptic diversity and fragmented distributions.
Mohammad Faridi +4 more
doaj +2 more sources
Vaccines, 2021 The genetic diversity and frequent emergence of novel genetic variants of porcine reproductive and respiratory syndrome virus type-2 (PRRSV) hinders control efforts, yet drivers of macro-evolutionary patterns of PRRSV remain poorly documented.
Igor A. D. Paploski +10 more
doaj +2 more sources
Microbiology Spectrum, 2023 Porcine reproductive and respiratory syndrome virus (PRRSV) is an important swine pathogen affecting the global swine industry. The first open reading frame 5 (ORF5)-based genetic lineage classification system describing global PRRSV-2 genetic diversity ...
Wannarat Yim-im +8 more
doaj +2 more sources