Results 11 to 20 of about 533,076 (344)
Systems genetic analysis of osteoblast-lineage cells. [PDF]
PLoS Genetics, 2012 The osteoblast-lineage consists of cells at various stages of maturation that are essential for skeletal development, growth, and maintenance. Over the past decade, many of the signaling cascades that regulate this lineage have been elucidated; however ...
Gina Calabrese +8 more
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Building a lineage from single cells: genetic techniques for cell lineage tracking [PDF]
Nature Reviews Genetics, 2017 Resolving lineage relationships between cells in an organism is a fundamental interest of developmental biology. Furthermore, investigating lineage can drive understanding of pathological states, including cancer, as well as understanding of developmental pathways that are amenable to manipulation by directed differentiation.
Mollie B. Woodworth +2 more
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Genetic signatures of lineage fusion closely resemble population decline [PDF]
Ecology and Evolution, 2023 AbstractAccurate interpretation of the genetic signatures of past demographic events is crucial for reconstructing evolutionary history. Lineage fusion (complete merging, resulting in a single panmictic population) is a special case of secondary contact that is seldom considered.
Ryan C. Garrick
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Genetic Mosaics and the Germ Line Lineage [PDF]
Genes, 2015 Genetic mosaics provide information about cellular lineages that is otherwise difficult to obtain, especially in humans. De novo mutations act as cell markers, allowing the tracing of developmental trajectories of all descendants of the cell in which the new mutation arises.
Samuels, Mark E., Friedman, Jan M.
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Redefining the serotonergic system by genetic lineage [PDF]
Nature Neuroscience, 2008 Central serotonin-producing neurons are heterogeneous-differing in location, morphology, neurotoxin sensitivity and associated clinical disorders-but the underpinnings of this heterogeneity are largely unknown, as are the markers that distinguish physiological subtypes of serotonergic neurons.
Patricia, Jensen +5 more
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Genetic analysis distinguished new natural population and old plantations of Cryptomeria japonica
Trees, Forests and People, 2023 Natural forest is important not only for conserving genetic diversity, but also as a future breeding resource, especially for forestry tree species. Cryptomeria japonica is an important forestry tree species in Japan, but natural populations are limited.
Yunosuke Onuma +3 more
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Vaccines, 2021 The genetic diversity and frequent emergence of novel genetic variants of porcine reproductive and respiratory syndrome virus type-2 (PRRSV) hinders control efforts, yet drivers of macro-evolutionary patterns of PRRSV remain poorly documented.
Igor A. D. Paploski +10 more
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Genetic flux over time in the Salmonella lineage [PDF]
Genome Biology, 2007 Abstract Background DNA sequences that are shared between closely related organisms while being absent from their common ancestor and from sister lineages of that ancestor are likely to have been acquired by horizontal gene transfer.
Vernikos, Georgios S +2 more
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Heliyon, 2023 Introduction: The population structure of Mycobacterium tuberculosis complex (MTBC) in Ethiopia is diverse but dominated by Euro-American (Lineage 4) and East-African-Indian (Lineage 3) lineages.
Mulualem Agonafir +8 more
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Genetic diversity of Bacillus anthracis Ames lineage strains in China
BMC Infectious Diseases, 2020 Background Anthrax is an endemic disease that persists in the rural regions of China. The global genetic population structure of B.anthracis has also been defined by the canonical single-nucleotide polymorphisms (canSNP) and multiple-locus variable ...
Enmin Zhang +4 more
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