Results 81 to 90 of about 533,076 (344)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Lineage frequency time series reveal elevated levels of genetic drift in SARS-CoV-2 transmission in England [PDF]

open access: green, 2022
Qinqin Yu   +6 more
openalex   +1 more source

Listeriolysin S, a Novel Peptide Haemolysin Associated with a Subset of Lineage I Listeria monocytogenes [PDF]

open access: yes, 2008
peer-reviewedStreptolysin S (SLS) is a bacteriocin-like haemolytic and cytotoxic virulence factor that plays a key role in the virulence of Group A Streptococcus (GAS), the causative agent of pharyngitis, impetigo, necrotizing fasciitis and streptococcal
Casey, Patrick G.   +7 more
core   +4 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Pseudobarbus outeniqua sp. nov., a new redfin species (Teleostei, Cyprinidae) from the Cape Fold Ecoregion of South Africa [PDF]

open access: yesZooKeys
Previous DNA-based studies identified four genetic lineages within Pseudobarbus afer: (i) the Mandela lineage confined to the Sundays, Swartkops, and Baakens river systems, (ii) the Krom lineage endemic to the Krom River system, (iii) the St Francis ...
Fatah Zarei   +3 more
doaj   +3 more sources

Prevention of urinary tract infection in spinal cord-injured patients: safety and efficacy of a weekly oral cyclic antibiotic (WOCA) programme with a 2 year follow-up--an observational prospective study.

open access: yes, 2006
POPULATION: Spinal cord injury (SCI) patients with neurogenic bladder have an increased risk for symptomatic urinary tract infection (UTI). Recurrent UTI requires multiple courses of antibiotic therapy, markedly increasing the incidence of multidrug ...
Bernard, Louis   +6 more
core   +1 more source

Discordance Between Mitochondrial and Nuclear Contact Zones Within Antelope Ground Squirrels (Ammospermophilus) [PDF]

open access: yes, 2020
A common biogeographic pattern found in many co-distributed species along the Baja California peninsula is the genetic divergence in the Vizcaíno Desert.
Gray, Shannon
core  

Genetic investigation within Lactococcus garvieae revealed two genomic lineages [PDF]

open access: yesFEMS Microbiology Letters, 2012
The diversity of a collection of 49 Lactococcus garvieae strains, including isolates of dairy, fish, meat, vegetable and cereal origin, was explored using a molecular polyphasic approach comprising PCR-ribotyping, REP and RAPD-PCR analyses and a multilocus restriction typing (MLRT) carried out on six partial genes (atpA, tuf, dltA, als, gapC, and galP).
C. Ferrario   +4 more
openaire   +3 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Mitochondrial DNA Variation of Feral Honey Bees (Apis mellifera L.) from Utah (USA)

open access: yesJournal of Apicultural Science, 2018
A study was conducted on the mitochondrial DNA genetic diversity of feral colonies and swarms of Apis mellifera from ten counties in Utah by sequencing the intergenic region of the cytochrome oxidase (COI-COII) gene region.
Cleary Dylan   +5 more
doaj   +1 more source

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