Results 141 to 150 of about 36,759 (336)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Synthesis of regional crust and upper-mantle structure from seismic and gravity data [PDF]

open access: yes
Analyses of regional gravity and magnetic patterns, LANDSAT images and geological information revealed two major lineaments crossing western Pennsylvania and parts of surrounding states.
Alexander, S. S., Lavin, P. M.
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Tectonic Structure of Alaska as Evidenced by ERTS Imagery and Ongoing Seismicity [PDF]

open access: yes
The author has identified the following significant results. A mosaic was constructed from selected portions of eleven LANDSAT images at a scale of 1:1,000,000. Band 7 images were utilized because of their superior haze-cutting characteristics.
Gedney, L. D.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Relationship of roof falls in underground coal mines to fractures mapped on ERTS-1 imagery [PDF]

open access: yes
ERTS imagery is of unique value for mapping of certain fractures that are not identifiable on aircraft imagery. Because color infrared and ERTS imagery complement each other both sources of data were used to map fractures in western Indiana and eastern ...
Amato, R. V.   +4 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Determining stress states using dike swarms: The Lauma Dorsa example [PDF]

open access: yes
Initial examination of the Magellan coverage of Venus has revealed between 150 and 300 large, radially lineated landforms distributed across the planet's surface.
Grosfils, Eric B., Head, James W., III
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

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